Results 61 to 70 of about 962,469 (222)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Simultaneous Acute Appendicitis and Isolated Common Iliac Artery Aneurysm: A Case Report
Clinical Case ReportsThis case report presents the rare simultaneous occurrence of acute appendicitis and a large right common iliac artery aneurysm in a 69‐year‐old male with a history of diabetes and hypertension.
Meghdad Ghasemi Gorji +4 more
doaj +1 more source
, 2012 We investigate how suitable a weighted network is for gossip spreading. The proposed model is based on the gossip spreading model introduced by Lind et.al. on unweighted networks.
Barabasi A. L. +10 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Earth microbial co-occurrence network reveals interconnection pattern across microbiomes
Microbiome, 2020 Background Microbial interactions shape the structure and function of microbial communities; microbial co-occurrence networks in specific environments have been widely developed to explore these complex systems, but their interconnection pattern across ...
Bin Ma +11 more
doaj +1 more source
Word Sense Disambiguation by Web Mining for Word Co-occurrence Probabilities [PDF]
, 2004 This paper describes the National Research Council (NRC) Word Sense Disambiguation (WSD) system, as applied to the English Lexical Sample (ELS) task in Senseval-3.
Turney, Peter D.
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Ischemic heart disease and metabolic dysfunction–associated steatotic liver disease represent significant global health challenges, characterized by overlapping pathophysiological mechanisms.
Wei Wang +8 more
doaj +1 more source
A co-occurrence framework conceptualized for bridging the gap between basic science, clinical research and clinical practices [PDF]
, 2016 The intellectual impulsiveness of man to understand the unknown and the continual need of the society to improve healthcare have encouraged extensive investigation on numerous and diverse cause-and-effect relationships.
Hsu, Michael Chih-Yuan
core +1 more source