Results 91 to 100 of about 9,219,250 (287)

Analysis of co-authorship network and thematic pattern of the articles in the Journal of Public Management Researches [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2020
Background and aim: In recent years, journals and quarterly journals have placed a great emphasis on increasing scientific collaboration in articles.
Arman Bahari, Behnoosh Moody
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Scientific Map Analysis and Visualization of Articles Published In the Journal of Research in School and Virtual Learning Using the Social Networks Analysis Approach [PDF]

open access: yesپژوهشنامه علم سنجی
Purpose: Today, with the advancement of communication technologies, particularly the Internet, we are witnessing the generation of a vast amount of information.
Mostafa Akhavan-Safar   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A scientometrics study on informetrics: one decade quantitative researches in Iran (2002-2012)

open access: yesمجله علم‌سنجی کاسپین, 2014
Background and aim: Present scientometrics study aimed at investigating the scientific collaboration of Iranian scientometrics researchers during 2002-2012.
Reza Basirian jahromi, Ehsan Geraei
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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