Results 121 to 130 of about 421,786 (290)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Designing Interaction for Co-creation [PDF]
, 2017 This paper describes several compositions of live, interactive electronics where mutual listening between the performer and the computer form the basis for the interaction. The electronics combines algorithmically defined musical-logic with inputs from the performer.
openaire +1 more source
STRATEGIES FOR INCREASING MARKETING FLEXIBILITY: AN APPLICATION OF THE SERVICE DOMINANT LOGIC [PDF]
The paper outlines the necessity of marketing flexibility in the context of new theoretical and practical conditions, and proposes a synthetic model of flexible marketing systems capable to enhance the value co-creation process.marketing flexibility, the
Gurau Calin
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundShiga toxin-producing Escherichia coli (STEC) is a leading foodborne pathogen responsible for hemolytic uremic syndrome (HUS). This pathogen poses a severe threat to global public health.
Baili Zheng +8 more
doaj +1 more source
PENGARUH CO-CREATION EXPERIENCES TERHADAP IDENTITAS KABUPATEN GARUT SERTA DAMPAKNYA PADA KEPUTUSAN BERKUNJUNG : Survei terhadap Wisatawan Nusantara yang Berkunjung ke Kabupaten Garu [PDF]
, 2013 Wisatawan memiliki peran sentral selaku pembuat keputusan untuk mengunjungi suatu tempat wisata tertentu. Namun jumlah kunjungan wisata ke Kabupaten Garut relatif fluktuatif.
Lestari, Fitri
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Customer engagement and value co-creation [PDF]
, 2015 Contemporary markets are increasingly interconnected , with actors no longer seen as part of linear value chains but existing in networks of service systems where interaction, collaboration and experience sharing take place (Jaakkola, Helkkula & Aarikka -
Alexander, Matthew, Jaakkola, Elina
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source