Results 111 to 120 of about 1,569,415 (306)

Contradictions in Value Co-Creation in IT-Enabled Services: A Case of Geocaching [PDF]

, 2014
Negative consequences of value co-creation in consumer information systems are rarely assessed in information systems (IS) research. In this empirical case study, we focus on contradictions and structural tensions in information technology (IT)-enabled ...
Tuunanen, Tuure, Vartiainen, Tero
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

What’s So Special About Patent Law? [PDF]

, 2016
The widespread belief that patent law is special has shaped the development of patent law into one of the most specialized areas of the law today. The belief in patent law’s exceptionalism manifests itself as two related presumptions with respect to the ...
Brook, Gary, DE SMET, Nathalie, Doyen, Pierre, Hermans, Emmanuel, Pochet, Amandine, van Neerven, Sabien, Vergouts, Maxime   +6 more
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Research on User Experience of Hotel Service Robots from the Perspective of Human–Machine Collaborative Value Creation

Systems
Although research on hotel service robots has been continuously increasing, the existing literature still lacks a systematic exploration of the multiple concurrent mechanisms involved in the formation of user experience.
Xiaoqian Lu, Shenglan Li
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Enhancing customer value co-creation through online brand interactivity: A comparative analysis of search-hedonic and experience-hedonic products [PDF]

Innovative Marketing
This study investigates how online brand interactivity fosters customer value co-creation, a collaborative process in which consumers actively contribute to co-creating value, by enhancing brand experiences at both individual and community levels ...
Rae Secioria, Adi Zakaria Afiff, Sri Rahayu Hijrah Hati, Muhammad Gunawan Alif   +3 more
doaj   +1 more source

The importance of person-centred care and co-creation of care for the well-being and job satisfaction of professionals working with people with intellectual disabilities [PDF]

, 2017
Background: Person-centred care and co-creation of care (productive interactions between clients and professionals) are expected to lead to better outcomes for clients.
Avgar, Berghout, Bhatnagar, Cramm, Cramm, Devereux, Ducharme, Ford, Gerteis, Gerteis, Gittell, Gray-Stanley, Haile, Hatton, Hatton, Kivimaki, Linn, Mansell, Nieboer, Rathert, Rathert, Saane, Schermerhorn, Schuengel, Shaddock, Skirrow, Traynor, Weinberg, Willems   +28 more
core   +3 more sources

Managing the experience co-creation in tourism

, 2014
La co-creazione è oramai riconosciuto in letteratura quale processo in grado di incidere positivamente sulla soddisfazione del consumatore e, di conseguenza, sul successo delle aziende. Nonostante ciò, gli studi teorici ed empirici su questa tematica sono ancora in una fase embrionale e il potenziale della co-creazione è ancora non del tutto esplorato.
openaire   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source