Results 201 to 210 of about 2,001,286 (262)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Seeing both sides of the story: creating patient/provider persona dyads for use in mental health service co-design. [PDF]

Res Involv Engagem
Dominello A, Lu S, Clay-Williams R, Cheek C.   +3 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Co-design with Indigenous Peoples

Anderson, Kate, Butler, Tamara, Gall, Alana, Elder-Robinson, Elaina, Garvey, Gail   +4 more
openaire   +2 more sources

Model of care to promote recovery in older people with long COVID: findings from interviews and a co-design workshop. [PDF]

BMJ Open
Manuel K, Davis A, Little K, Peng F, Gwilt I, Laver K, Adey-Wakeling Z, Seaforth C, Crotty M.   +8 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Development of a Patient and Carer Advisory Board to Co-Design Health Services Research for the Quality of Care of People With Dementia. [PDF]

Health Expect
Bailey DX, Thompson J, Beattie E, Prudon P, Jack L, Lawson J, Lendich K, Miller E, Petrie G, Quinn J, Webb I, Gray LC, Martin-Khan M.   +12 more
europepmc   +1 more source

A Patient Bill of Rights and Responsibilities for Wound Prevention and Care in Canada: Grounded in Stories and Guided by Co-Design and Community-Based Participatory Principles. [PDF]

Int Wound J
Costa IG, Philips C, Stevens K, Schoales C, Bajnok I, Botros M, Strachan R, Santorelli S, Camargo-Plazas P.   +8 more
europepmc   +1 more source

'We gout your back': a qualitative study to co-design educational gout resources with Pacific people in Aotearoa New Zealand. [PDF]

Health Promot Int
Tu'akoi S, 'Ofanoa S, Tohi M, Pauuvale A, Heather M, Lutui H, Lamont R, Goodyear-Smith F, 'Ofanoa M.   +8 more
europepmc   +1 more source