Results 201 to 210 of about 1,996,608 (264)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Model of care to promote recovery in older people with long COVID: findings from interviews and a co-design workshop. [PDF]

BMJ Open
Manuel K, Davis A, Little K, Peng F, Gwilt I, Laver K, Adey-Wakeling Z, Seaforth C, Crotty M.   +8 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Development of a Cystic Fibrosis Weight Management Programme:  protocol for a co-design study. [PDF]

NIHR Open Res
Barrett J, Topping AE, Ntoumanis N, Turner AM, White H, Fenton SAM.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Maternal Health Literacy among Migrant Women: A Co-Design Study in Portugal. [PDF]

Port J Public Health
Gonçalves E, Dias S, Marques MJ.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Patient Bill of Rights and Responsibilities for Wound Prevention and Care in Canada: Grounded in Stories and Guided by Co-Design and Community-Based Participatory Principles. [PDF]

Int Wound J
Costa IG, Philips C, Stevens K, Schoales C, Bajnok I, Botros M, Strachan R, Santorelli S, Camargo-Plazas P.   +8 more
europepmc   +1 more source

'We gout your back': a qualitative study to co-design educational gout resources with Pacific people in Aotearoa New Zealand. [PDF]

Health Promot Int
Tu'akoi S, 'Ofanoa S, Tohi M, Pauuvale A, Heather M, Lutui H, Lamont R, Goodyear-Smith F, 'Ofanoa M.   +8 more
europepmc   +1 more source