Results 51 to 60 of about 63,643 (238)

Nanomaterials for co‐immobilization of multiple enzymes

BMEMat
AbstractIn order to co‐immobilize multiple enzymes, a wide range of nanomaterials has been designed to achieve synergistic enzyme activity and enhance catalytic efficiency. Nanomaterials, as carriers for enzyme co‐immobilization, possess various advantages such as tunable morphology and size, high specific surface area, and abundant chemically active ...
Jingyu Zhang, Jonathan F. Lovell, Jiafu Shi, Yumiao Zhang   +3 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes

Chemistry – A European Journal
Abstract Advanced clinical trials investigate the Psilocybe magic mushroom natural product psilocybin as a treatment against major depressive disorder. Currently, synthetic material is used to meet the demand for legitimate pharmaceutical purposes.
Schäfer, Tim, Sherwood, Alexander, Kirkland, Thomas, Krüger, Thomas, Worbs, Jakob, Kniemeyer, Olaf, Gressler, Markus, Hoffmeister, Dirk   +7 more
openaire   +2 more sources

Co-immobilized recombinant glycosyltransferases efficiently convert rebaudioside A to M in cascade

RSC Advances, 2021
Biotransformation of Reb A to Reb D and Reb M by recombinant glycosyltransferases immobilized on chitosan beads.
Zhenyang Wang, Wenbin Liu, Wei Liu, Yuanyuan Ma, Yatong Li, Baoqi Wang, Xiaozhen Wei, Zhiming Liu, Hao Song   +8 more
openaire   +3 more sources

A Protocol for Custom Biomineralization of Enzymes in Metal–Organic Frameworks (MOFs)

Bio-Protocol
Enzyme immobilization offers a number of advantages that improve biocatalysis; however, finding a proper way to immobilize enzymes is often a challenging task.
Zoe Armstrong, Drew Jordahl, Austin MacRae, Qiaobi Li, Mary Lenertz, Patrick Shen, Anastasiia Botserovska, Li Feng, Angel Ugrinov, Zhongyu Yang   +9 more
doaj   +1 more source

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis

eLife, 2016
The importance of mechanical activity in the regulation of muscle progenitors during chick development has not been investigated. We show that immobilization decreases NOTCH activity and mimics a NOTCH loss-of-function phenotype, a reduction in the ...
Joana Esteves de Lima, Marie-Ange Bonnin, Carmen Birchmeier, Delphine Duprez   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Evaluation of the Protein Profile of a Saccharomyces cerevisiae Strain Immobilized in Biocapsules for Use in Fermented Foods

Foods
Yeast biocapsules are a novel immobilization technology that could be used in fermentation processes. They are spherical structures consisting of yeast cells encapsulated and attached to the hyphae of a filamentous fungus.
Juan C. García-García, Miguel E. G-García, Juan C. Mauricio, Juan Moreno, Teresa García-Martínez   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source