Results 121 to 130 of about 7,545,643 (384)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Seroprevalence of hepatitis B virus and its co-infection with hepatitis D virus and hepatitis C virus in Iranian adult population [PDF]

, 2007
Context: Hepatitis B virus (HBV) infection is one of the most prevalent public health problems worldwide (especially in developing countries). Aims: This study was carried out to determine the seroprevalence of HBV and its co-infection with hepatitis D ...
Abbasali, K., Abdolvahab, M., Danyal, R., Gholamreza, R., Hamidreza, J., Khodaberdi, K., Nafiseh, A., Shahryar, S.   +7 more
core  

An observational cohort study of bacterial co-infection and implications for empirical antibiotic therapy in patients presenting with COVID-19 to hospitals in North West London

Journal of Antimicrobial Chemotherapy, 2020
Objectives To describe the prevalence and nature of bacterial co-infections in COVID-19 patients within 48 hours of hospital admission and assess the appropriateness of empirical antibiotic treatment they received.
Liyang Wang, A. K. Amin, P. Khanna, Adnan Aali, A. McGregor, P. Bassett, G. Gopal Rao   +6 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Cross-sectional study of the burden of vector-borne and soil-transmitted polyparasitism in rural communities of Coast Province, Kenya. [PDF]

, 2014
BACKGROUND: In coastal Kenya, infection of human populations by a variety of parasites often results in co-infection or poly-parasitism. These parasitic infections, separately and in conjunction, are a major cause of chronic clinical and sub-clinical ...
Bisanzio, D, Bustinduy, AL, King, CH, Kitron, U, Muchiri, EM, Mungai, PL, Mutuku, F   +6 more
core   +7 more sources

COVID‐19 and herpes zoster co‐infection presenting with trigeminal neuropathy

European Journal of Neurology, 2020
Background Varicella‐zoster virus (VZV) is a human neurotropic virus that remains in a latent state within ganglionic neurons throughout the entire neuroaxis after the primary infection.
Ana Carolina Andorinho de Freitas Ferreira, T. Romão, Yuri SIlva Macedo, C. Pupe, Osvaldo J. M. Nascimento   +4 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Case report: Detection of non-O1/non-O139 Vibrio cholerae in a patient with hepatic space-occupying lesions using metagenomic next-generation sequencing

Frontiers in Medicine
Introduction/backgroundVibrio cholerae is the causative agent of the human intestinal infectious disease cholera, which includes a variety of serogroups.
Wei Zhang, Li Xiao, Xingxing Shan, Bing Dai, Chunyan Tang, Jianchun Xian, Yan Yu   +6 more
doaj   +1 more source

Short-term treatment outcomes in human immunodeficiency virus type-1 and hepatitis B virus co-infections [PDF]

, 2016
BACKGROUND: Co-infection of HIV with HBV is common in West Africa but little information is available on the effects of HBV on short-term therapy for HIV patients.
Adiku, Theophilus Korku, Agyei, Afrakoma Adjoa, Arens, Max, Duedu, Kwabena Obeng, Lartey, Margaret, MIngle, Julius Abraham Addo, Sagoe, Kwamena William Coleman, Ziga, Francesca   +7 more
core   +2 more sources

Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV

Clinical Infectious Diseases, 2020
The effect of host immune status on SARS-CoV-2 infection remains unknown. Here, we report the first case of COVID-19 with HIV-1 and HCV co-infection, who showed a persistently negative SARS-CoV-2 RNA test, but delayed antibody response in the plasma ...
Juanjuan Zhao, X. Liao, Haiyan Wang, Lanlan Wei, Mingzhao Xing, Lei Liu, Zheng Zhang   +6 more
semanticscholar   +1 more source