Results 101 to 110 of about 10,517,441 (314)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

CHAIN QUALITY MANAGEMENT IN CO-OPERATIVES

This paper investigates the relationship between the chosen quality strategy and the vertical co-ordination mechanism of a focal company by using new institutional economics, as well as strategic management approaches. The theoretical findings are tested
Hanf, Jon Henrich, Pieniadz, Agata
core  

Karte der Gilbert oder Kingsmill In. [cartographic material] : nach den neusten Quellen u. privaten Notizen /

, 1879
Plate 5 from: [Maps of Oceania by L.Friederichsen & Co., probably published in Mitteilungen der Geographischen Gesellschaft in Hamburg, 1879]. Hamburg : L. Friederichsen & Co., 1879.; Map of Gilbert Islands (Kiribati).
L. Friederichsen & Co.
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Karte der Ansiedelungen am Hafen von Apia, Insel Upolo [cartographic material] /

, 1879
Plate 3 from: [Maps of Oceania by L.Friederichsen & Co., probably published in Mitteilungen der Geographischen Gesellschaft in Hamburg, 1879]. Hamburg : L. Friederichsen & Co., 1879.; Map of Apia, Samoa.
L. Friederichsen & Co.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Management of fishing of the Broadband Anchovy (Anchoviella lepidentostole) (Fowler, 1911), in south São Paulo State, Brazil

Brazilian Journal of Biology
The broadband anchovy (Anchoviella lepidentostole) is one of the most important fishery resources for economic and social development of Iguape City and for the whole of the south coast of São Paulo state.
JT. Mendonça, RP. Sobrinho
doaj   +1 more source

Real-time co-ordinated resource management in a computational enviroment

, 2003
Design co-ordination is an emerging engineering design management philosophy with its emphasis on timeliness and appropriateness. Furthermore, a key element of design coordination has been identified as resource management, the aim of which is to ...
Whitfield, R.I., Duffy, A.H.B., Coates, G., Hills, W.   +3 more
core  

Information systems management maturity and information technology security effectiveness [PDF]

, 2004
vii, 129 leaves ; 29 cm.Modern societies rely on Information Systems (IS), yet their protection has long been considered ineffective. Researchers and practitioners have struggled to understand the persistence of this phenomenon, but both agree that IS ...
Spicer, Garry, University of Lethbridge. Faculty of Management   +1 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source