Results 61 to 70 of about 932,353 (284)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Distinguishing Antonyms and Synonyms in a Pattern-based Neural Network
, 2017 Distinguishing between antonyms and synonyms is a key task to achieve high performance in NLP systems. While they are notoriously difficult to distinguish by distributional co-occurrence models, pattern-based methods have proven effective to ...
Nguyen, Kim Anh +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Bayesian derived network of breast pathology co-occurrence
Journal of Biomedical Informatics, 2008 In this paper, we present the validation and verification of a machine-learning based Bayesian network of breast pathology co-occurrence. The present/not present occurrences of 29 common breast pathologies from 1631 pathology reports were used to build the network. All pathology reports were developed by a single pathologist.
Maskery, Susan M. +4 more
openaire +2 more sources
Exploring the random genesis of co-occurrence networks [PDF]
Physica A: Statistical Mechanics and its Applications, 2011 Using the network random generation models from (Gustedt 2009), we simulate and analyze several characteristics (such as the number of components, the degree sequence and the clustering coefficient) of the generated networks. This is done for a variety of distributions (fixed value, Bernoulli, Poisson, binomial) that are used to control the parameters ...
Jens Gustedt +2 more
openaire +1 more source
Analysis of pain research literature through keyword Co-occurrence networks
PLOS Digital Health, 2023 Pain is a significant public health problem as the number of individuals with a history of pain globally keeps growing. In response, many synergistic research areas have been coming together to address pain-related issues. This work reviews and analyzes a vast body of pain-related literature using the keyword co-occurrence network (KCN) methodology. In
Burcu Ozek +4 more
openaire +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Visualising text co-occurrence networks [PDF]
, 2016 We present a tool for automatically generating a visual summary of unstructured text data retrieved from documents, web sites or social media feeds. Unlike tools such as word clouds, we are able to visualise structures and topic relationships occurring in a document. These relationships are determined by a unique approach to co-occurrence analysis. The
Hirsch, Laurie, Andrews, Simon
openaire
Deciphering microeukaryotic–bacterial co-occurrence networks in coastal aquaculture ponds
Marine Life Science & Technology, 2023 AbstractMicroeukaryotes and bacteria are key drivers of primary productivity and nutrient cycling in aquaculture ecosystems. Although their diversity and composition have been widely investigated in aquaculture systems, the co-occurrence bipartite network between microeukaryotes and bacteria remains poorly understood.
Zheng, Xiafei +6 more
openaire +2 more sources
Global Ecology and ConservationThe implementation of ecological restoration projects, such as wetland rehabilitation, is essential for achieving sustainable development. However, current research on monitoring recovery status primarily focuses on evaluating water quality and aquatic ...
Jiamin Liu +5 more
doaj +1 more source