Results 81 to 90 of about 3,752,368 (307)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Co-operative Development and Corporate Governance Structures in German Co-operatives: Problems and Perspectives [PDF]

open access: yes
In Germany exist a large number of co-operatives that are engaged in a broad variety of business activities. Their organisational structure is determined by co-operative law and to a lesser degree by statutes or by-laws.
Kramer, Jost W.
core  

Health care co-operatives in South Korea : an effective alternative to the health care system in the future? [PDF]

open access: yes, 2013
textSouth Korea has been evaluated as having the weakest primary care system. In South Korea, the health care delivery system is concentrated too heavily in the private sector.
No, Won, active 2013
core  

Co-operative Transport System and investigation of the co-operation

open access: yesPeriodica Polytechnica Transportation Engineering, 2009
This paper deals with Intelligent Transport Systems (ITS) and the concept of a Co-operative Transport System (CTS), in which the communication and the knowledge sharing is much more important. This distributed knowledge allows improving road transport operations more safety and efficiency. After showing some issues about development and advantages of a
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

An in depth analysis of the development of the taxation of co-operatives in South Africa and whether this aligns with their economic purpose.

open access: yes, 2012
Includes abstract.Includes bibliographical references.In this study, after providing background on the co-operative movement both internationally and in the South African context and an indication of what the success of the co-operative sector could mean
Wheeler, Tracy Lyn
core  

Robust Collective Action by Farm Producers: Analyzing Co-Operatives as Common Property Institutions

open access: yesInternational Journal of the Commons
Common property institutions are often analyzed with Ostrom’s design principles, yet there are few applications of the analytical framework to institutions owned and controlled by organized farm producers (i.e. farm producer co-operatives). Applicable to
Jasper Grashuis
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Credit Co-operatives in Locally Financed Economic Development: Using Energy Efficiency as a Lever [PDF]

open access: yes
development finance, local economic development, energy efficiency, credit co ...
McIntyre, Robert J.
core  

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