Results 41 to 50 of about 31,900 (295)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Halogen and Hydrogen Bonding in Povidone-Iodine and Related Co-Phases [PDF]

open access: yesCrystal Growth & Design, 2017
Povidone-iodine is a widely used antiseptic and on the World Health Organization’s List of Essential Medicines. We report the X-ray crystal structure of a two-monomer unit model compound showing that the structure of povidone-iodine comprises protonated pyrrolidone units linked by intermolecular hydrogen bonds along with triiodide anions.
Melissa J. Goodwin   +5 more
openaire   +2 more sources

Consortia Building and Electronic Licensing as Vehicles for Re-Engineering Academic Library Services: The Case of the Technical Knowledge Center and Library of Denmark (DTV)

open access: yesIssues in Science and Technology Librarianship, 1999
The Technical Knowledge Center and Library of Denmark (DTV) has broken the vicious circle of zero growth funding, price increases, and journal cancellations. It required concentrated efforts in consortia building, electronic licensing, phasing out paper
Lars Bjørnshauge
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Can we predict the duration of an interglacial? [PDF]

open access: yesClimate of the Past, 2012
Differences in the duration of interglacials have long been apparent in palaeoclimate records of the Late and Middle Pleistocene. However, a systematic evaluation of such differences has been hampered by the lack of a metric that can be applied ...
P. C. Tzedakis   +6 more
doaj   +1 more source

Understanding social innovation in local energy transitions processes: A multi-case study

open access: yesGlobal Transitions, 2021
Social innovation (SI) in local energy transitions is gaining focus in current times but energy transitions have not yet been explicitly analysed in the context of SI.
Sujeetha Selvakkumaran, Erik O. Ahlgren
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Impact of intake conditions on characteristics of combustion of the HCCI engine using PRF80

open access: yesCogent Engineering
Recently, research on internal combustion engines has focused on mitigating and reducing pollution emissions and fuel consumption. Homogeneous charge compression ignition (HCCI) is a promising solution.
Tung Lam Nguyen, Van Thanh Ngo
doaj   +1 more source

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