Results 81 to 90 of about 2,348,055 (243)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Viral infectious diseases severity: co-presence of transcriptionally active microbes (TAMs) can play an integral role for disease severity. [PDF]

Front Immunol, 2022
Yadav A, Pandey R.
europepmc   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Characterization of High-Risk HPV/EBV Co-Presence in Pre-Malignant Cervical Lesions and Squamous Cell Carcinomas. [PDF]

Microorganisms, 2022
Blanco R, Carrillo-Beltrán D, Muñoz JP, Osorio JC, Tapia JC, Burzio VA, Gallegos I, Calaf GM, Chabay P, Aguayo F.   +9 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Does co-presence affect the way we perceive and respond to emotional interactions? [PDF]

Exp Brain Res, 2021
Bachmann J, Zabicki A, Gradl S, Kurz J, Munzert J, Troje NF, Krueger B.   +6 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cross-Room CO₂-Based Presence Detection for Occupancy Profiling

IEEE Access
Control systems for building services, such as heating and cooling, often rely on fixed timing schemes. While such approaches are convenient, they make strong assumptions about room usage, often leading to inadequate comfort and energy efficiency.
Jelle Vanhaeverbeke, Emiel Deprost, Steven Verstockt, Sofie van Hoecke   +3 more
doaj   +1 more source

What makes the psychosis 'clinical high risk' state risky: psychosis itself or the co-presence of a non-psychotic disorder? [PDF]

Epidemiol Psychiatr Sci, 2021
Hasmi L, Pries LK, Ten Have M, de Graaf R, van Dorsselaer S, Bak M, Kenis G, Richards A, Lin BD, O'Donovan MC, Luykx JJ, Rutten BPF, Guloksuz S, van Os J.   +13 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source