Results 81 to 90 of about 1,100,611 (301)
Formulation development of pharmaceutical products is often subjected to trials and errors, and to find the best formulary could be time consuming and financially wasteful. Factorial experimental design has been proposed to optimized formulation of pharmaceutical products. In this study a 23 factorial experimental design has been used to quantitatively
Oyeniyi, Yinka J. +1 more
openaire +2 more sources
The co-processing of coal with heavy feedstocks
Abstract When coal is processed with bitumen, heavy oils and petroleum residua there is a technological and economical advantage over conventional liquefaction processes. “Current coal” liquefaction concepts use, as vehicle, a coal-derived oil to react with coal, but because two-thirds of the coal-derived oil must be recycled, the throughput ...
James G. Speight, Speros E. Moschopedis
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Enzymatic hydrolysis of lignocellulose for bioethanol production shows a great potential to remit the rapid consumption of fossil fuels, given the fact that lignocellulose feedstocks are abundant, cost-efficient, and renewable.
Yufeng Yuan +6 more
doaj +1 more source
Cooperative Downlink Multicell Preprocessing Relying on Reduced-Rate Back-Haul Data Exchange [PDF]
Different-complexity multicell preprocessing (MCP) schemes employing distributed signal-to-interference leakageplus-noise ratio (SILNR) precoding techniques are proposed, which require reduced back-haul data exchange in comparison with the conventional ...
Hanzo, Lajos, Zhang, Rong
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
[Objective] Insufficient dissolution or shearing of drag reducing agents(DRAs) in product oil during pipeline transmission can have a significant impact on the oil's quality and may even result in quality accidents.
LIU Qian, LEI Bin, XIN Shihao, YANG He
doaj +1 more source
Encapsulation of water insoluble drugs in mesoporous silica nanoparticles using supercritical carbon dioxide [PDF]
Mesoporous silica nanoparticles MCM – 41 were synthesized with two dimensional hexagonal p6mm symmetry, high specific surface area(~ 980m2/g) narrow pore size and an average particle size of 186 nm.
Chirmade, U. N. +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

