Results 111 to 120 of about 1,797,050 (302)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Co-production on the Edge of Project and Process Management - The Sijtwende development project [PDF]
The goal of this paper is to describe and analyze co-production in public private partnerships in spatial planning. We will describe one specific case study, the location development project Sijtwende on the edge of two municipalities (The Hague and ...
Geert Teisman, Jurian Edelenbos
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Restructuring and rescaling water governance in mining contexts: the co-production of waterscapes in Peru [PDF]
, 2012 The governance of water resources is prominent in both water policy agendas and academic scholarship. Political ecologists have made important advances in reconceptualising the relationship between water and society.
Budds, Jessica, Hinojosa, Leonith
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Co-production : a defence of young people [PDF]
, 2018 Recent years have seen fundamental and challenging changes in the delivery of services for young people. Outcomes, outputs and interventions have become the language of service evaluations, and allocation of funding creating an instrumental environment ...
Gornall, Lesley
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Mechanism of Water Film Acting on Capillary Force in Porous Media of Tight Reservoirs
Liaoning Shiyou Huagong Daxue xuebaoThe water film formed within the pores of tight reservoirs leads to a distinct "oil⁃core water⁃film" configuration in the distribution of oil and water within the porous medium, which has a significant impact on the flow channels and capillary forces of ...
Xiaoxu DAI +4 more
doaj +1 more source
International Journal of Health Policy and ManagementThe editorial by Rycroft-Malone and colleagues highlights the fact that despite considerable efforts, knowledge translation and implementation sciences fail to have the desired impact on practice, policy and service delivery. As integrated knowledge translation and co-production/co-design academics, we resonated with several themes relevant to our own ...
Jacqui Cameron, Renee Fiolet
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Co-production of the car as a ‘service': involving customers in the value chain [PDF]
This article is dealing with a possible scenario for the future of the automobile thanks to the shift from an artefact vision to a services vision by which the customer might be involved as a true partner in the design of cars.
Jean-Jacques Chanaron +2 more
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