Results 101 to 110 of about 1,797,050 (302)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

El enfoque de coproducción de valor en la relación cliente-proveedor [PDF]

, 2005
It is a fact that the competitiveness of the firms depends on its hability to create sustainable competitive advantages, being the value creation one of its fundamental pillars.
Brândao, Elísio (Coordinador), Cauzo Bottala, Lourdes, Díez de Castro, Enrique Carlos (Coordinador), Picón Berjoyo, Araceli, Ruiz Moreno, Carolina   +4 more
core   +3 more sources

Effects of shearing at housing, grass silage feed value and extended grazing herbage allowance on ewe and subsequent lamb performance

Animal, 2009
The study involved 120 crossbred ewes (sixty 1.5 years old animals and sixty 2.5 years old animals; initial liveweight 67.6 kg, condition score 3.7), that were mated in October.
T.W.J. Keady, J.P. Hanrahan
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Reuse treatment technology of fracturing backflow fluid and its application in Wuqi Oilfield

Gongye shui chuli
The fracturing backflow fluid in Wuqi(WQ) Oilfield has problems such as large quantity, high viscosity, and difficult treatment, and the environmental situation is extremely severe.
CHEN Gang, WANG Weilong, YANG Shuisheng, LI Chen, ZHU Jinyan, SHEN Taizhi, HONG Xi   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Research on key technology of packer rubber barrel for integrated fracturing and completion of gas well

Journal of Petroleum Exploration and Production Technology
The staged and layered fracturing technology plays an important role in unconventional tight reservoirs. And the gas well fracturing and completion integration is the core component to realize the fracturing and completion integration process, which can ...
Peng Wang, Meng Cai, Zhaoyi Liu, Wenhai Ma, Junliang Li   +4 more
doaj   +1 more source

A Combined Immersed Boundary Method for Flows with Scalar Transport

Journal of Chemical Engineering of Japan
A solid volume fraction type immersed boundary method and a ghost cell immersed boundary method are combined for solving flows with scalar transport such as concentration of chemical species and heat.
Yuta Yaegashi, Hiroki Muramatsu, Naoki Shimada, Yusuke Uchihashi, Mako Sato   +4 more
doaj   +1 more source

Co-production of substitutable products [PDF]

, 1989
Includes bibliographical references (p. 24-25).Research partially supported by The Leaders for Manufacturing Program.Gabriel R.

core