Results 81 to 90 of about 1,816,176 (258)

Reuse treatment technology of fracturing backflow fluid and its application in Wuqi Oilfield

Gongye shui chuli
The fracturing backflow fluid in Wuqi(WQ) Oilfield has problems such as large quantity, high viscosity, and difficult treatment, and the environmental situation is extremely severe.
CHEN Gang, WANG Weilong, YANG Shuisheng, LI Chen, ZHU Jinyan, SHEN Taizhi, HONG Xi   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on key technology of packer rubber barrel for integrated fracturing and completion of gas well

Journal of Petroleum Exploration and Production Technology
The staged and layered fracturing technology plays an important role in unconventional tight reservoirs. And the gas well fracturing and completion integration is the core component to realize the fracturing and completion integration process, which can ...
Peng Wang, Meng Cai, Zhaoyi Liu, Wenhai Ma, Junliang Li   +4 more
doaj   +1 more source

A Combined Immersed Boundary Method for Flows with Scalar Transport

Journal of Chemical Engineering of Japan
A solid volume fraction type immersed boundary method and a ghost cell immersed boundary method are combined for solving flows with scalar transport such as concentration of chemical species and heat.
Yuta Yaegashi, Hiroki Muramatsu, Naoki Shimada, Yusuke Uchihashi, Mako Sato   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The ‘co’ in co-production

Science Museum Group Journal, 2016
Dr Helen Graham
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Delayed autumn closing and its effects on silage dry matter production and sward quality

Irish Journal of Agricultural and Food Research
The effects of delayed autumn closing of perennial ryegrass-based swards on silage dry matter production and quality from first cut silage harvest the following season were evaluated in a plot experiment conducted at Hillsborough, Northern Ireland.
E.J. Meehan, K.M. Huson, N. Grant, L.E. Chesney, J.D. Patterson   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source