Results 81 to 90 of about 1,753,884 (256)
Journal of Petroleum Exploration and Production TechnologyThe staged and layered fracturing technology plays an important role in unconventional tight reservoirs. And the gas well fracturing and completion integration is the core component to realize the fracturing and completion integration process, which can ...
Peng Wang +4 more
doaj +1 more source
A Combined Immersed Boundary Method for Flows with Scalar Transport
Journal of Chemical Engineering of JapanA solid volume fraction type immersed boundary method and a ghost cell immersed boundary method are combined for solving flows with scalar transport such as concentration of chemical species and heat.
Yuta Yaegashi +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Delayed autumn closing and its effects on silage dry matter production and sward quality
Irish Journal of Agricultural and Food ResearchThe effects of delayed autumn closing of perennial ryegrass-based swards on silage dry matter production and quality from first cut silage harvest the following season were evaluated in a plot experiment conducted at Hillsborough, Northern Ireland.
E.J. Meehan +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mechanism of Water Film Acting on Capillary Force in Porous Media of Tight Reservoirs
Liaoning Shiyou Huagong Daxue xuebaoThe water film formed within the pores of tight reservoirs leads to a distinct "oil⁃core water⁃film" configuration in the distribution of oil and water within the porous medium, which has a significant impact on the flow channels and capillary forces of ...
Xiaoxu DAI +4 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source