Results 221 to 230 of about 1,748,214 (284)

HEDGES co-prevents both SARS-CoV-2 and pandemic influenza infection in mice by rapid, durable co-production of twelve different anti-pandemic monoclonal antibodies. [PDF]

PLoS One
Mack M, Ye A, Ursu S, Ice R, Soroceanu L, Shoor S, McAllister S, Heath T, Handumrongkul C, Debs R.   +9 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Study on Preparation and Mechanism of High Temperature and High Salt Resistance Fluid Loss Reducer

ACS Omega
Bo Wang, Shengli Gong, Changlin Shi, Peng Hao, Yan Cheng, Baolu Li, Daoxiong Li   +6 more
doaj   +1 more source

Sustainable co-production of carbon quantum dots and activated carbon from natural rubber latex for the inhibition of pathogenic microorganisms and removal of pharmaceutical residues. [PDF]

RSC Adv
Yousatit S, Nuntang S, Yokoi T, Ngamcharussrivichai C, Hinchiranan N.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Investing in youth public mental health in India: multi-stakeholder co-production of a whole school program to promote the mental health of Indian adolescents. [PDF]

Front Public Health
Hugh-Jones S, Prabhu S, Arelingaiah M, Podiya J, Lakshman K, Nag R, Warriner L, Palmer A, Hudson K, Fazel M, Ventakaraman S, Cooke P, Mallikarjun P, Khandeparkar P, Bhola P, Navaneetham J.   +15 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Co-production in HIV research: a case study from the COVID-19 pandemic. [PDF]

Res Involv Engagem
Papageorgiou V, Bruton J, Johnson H, Petretti S, Thamm W, Anderson J, Hamza H, Ward H.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Co-production in sleep research: A scoping review of current practices and future directions. [PDF]

J Sleep Res
Gale EL, Manrai R, Caddick L, Murray A, Whalley HC, Smith D, Gardani M.   +6 more
europepmc   +1 more source