Results 51 to 60 of about 1,816,176 (258)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of Holstein–Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility

Animal, 2009
Pasture-based Holstein–Friesian cows from three genetic groups differing in the Irish ‘Economic Breeding Index’ (EBI) value and genetic background, namely North-American (NA) national average EBI genetic merit (LOW-NA, n = 42), North-American high EBI ...
G. Olmos, L. Boyle, B. Horan, D.P. Berry, R. Sayers, A. Hanlon, J.F. Mee   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effect of genetic group and feed system on locomotion score, clinical lameness and hoof disorders of pasture-based Holstein–Friesian cows

Animal, 2009
The aim of the present study was to determine the effect of the genetic group of the Holstein–Friesian (HF) and pasture-based feeding system (3 × 2 factorial arrangement) on locomotion score (six gait aspects scored from one to five), clinical lameness ...
G. Olmos, L. Boyle, B. Horan, D.P. Berry, P. O’Connor, J.F. Mee, A. Hanlon   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Numerical simulation of CO2-ECBM for deep coal reservoir with strong stress sensitivity

Heliyon
CH4 production rate of coalbed methane (CBM) well decreases rapidly during primary recovery in the deeply buried coal seam, resulting in a lot of CH4 residues.
Shengli Gong, Lu Zhang, Tongyao Zhang, Wei He, Weiqiang Hu, Hongchao Yin, Liangshuai Ma, Xin Hong, Wei Zhang, Bo Zhang   +9 more
doaj   +1 more source

Co-production: what makes co-production work? Evidence from Pakistan [PDF]

International Journal of Public Sector Management, 2016
Purpose – In developing countries there is a growing recognition that co-production offers more cost effective and responsive service delivery options in low income areas. The purpose of this paper is to explore the way co-production initiatives are managed in developing country, Pakistan.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Lithology identification of shale gas reservoirs using multi-source intelligent learning algorithms

Discover Applied Sciences
Lithology classification of shale gas reservoirs is pivotal for oil and gas exploration and development, as it directly dictates the reliability of reservoir evaluation, fracturing design, and productivity prediction.
Ming Chen, Longfei Sun, Li Hao, Wei Xiong, Lin Yang, Liwei Cui   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source