Results 41 to 50 of about 26,913,237 (296)

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

A bibliometric analysis of research on trade remedies [PDF]

Problems and Perspectives in Management
This study aims to explore the research landscape and identify the main research directions related to the topic of trade remedies. The research data were collected by accessing the Scopus database with 289 documents and the WoS database with 75 ...
Long Tran Viet, Hai Phan Thanh
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Worldwide researches on broiler breeders: A 25-year bibliometric review

Poultry Science
The poultry industry plays a key role in meeting global protein needs amid changing demographics and lifestyles, and is constantly growing and evolving. Genetic selection and optimization of broiler breeder flocks have been key drivers of growth, making ...
Omid Bouzari, Mahdi Zhandi, Sayyed Mohammad Hadi Hussaini   +2 more
doaj   +1 more source

Mapping child–computer interaction research through co-word analysis

International Journal of Child-Computer Interaction, 2020
This paper employs hierarchical clustering, strategic diagrams, and network analysis to construct an intellectual map of the Child–Computer Interaction research field (CCI) and to visualize the thematic landscape of this field using co-word analysis. This approach assumes that an article’s keywords constitute an adequate description of its content and ...
Michail N. Giannakos, Zacharoula K. Papamitsiou, Panos Markopoulos 0001, Janet C. Read, Juan Pablo Hourcade   +4 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research hotspots in pediatrics: co-word clustering analysis based on readership in PubMed Central

Frontiers in Pediatrics
ObjectiveBy analyzing high readership articles from the Chinese Journal of Contemporary Pediatrics (CJCP) in the PubMed Central (PMC) database, this study aims to identify research hotspots and trends in the field of pediatrics.MethodsArticles from the ...
Fangming Deng, Wen Sun, Jiangwei Guo, Yujia Yang   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Deriving word meanings from context: does explanation facilitate contextual analysis? [PDF]

, 2007
The ability to derive the meanings of words from supportive story contexts was studied in 45 seven-eight-year-olds. Children read short stories each containing a different novel word and defined the word at the end of each story.
Cain, Kate
core   +4 more sources