Results 61 to 70 of about 26,913,237 (296)

Analysis of Stomach Cancer Fields through Hierarchical Clustering Method

مدیریت اطلاعات سلامت, 2020
Introduction: Scientometric study is one of the efficient methods of academic evaluation in authentic databases. Hierarchical clustering is also a useful instrument in providing an overview of a studies in a field and understanding of its knowledge ...
Razieh Farshid, Faramarz Soheili, Hamed Gholami, Ehsan Geraei   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A keywords extraction algorithm optimized by integrating co-word analysis

Journal of Big Data
The paper proposed a keywords extraction optimization algorithm based on co-word analysis, named CATKE, to address the problems of the single dimension of word importance evaluation and relatively low precision of extracting keywords in the classic TF ...
Ran Huang
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Predicting co-word links via heterogeneous graph convolutional networks

Scientific Reports
Co-word analysis, which explores the co-occurrence of key terminology within a specific field, is a valuable tool for identifying research themes and their networks.
Yangmin Li, Xin Zhang, Xin Bai, Sen Bai, Zhengang Jiang   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Data for dynamical co-word analysis of science evolution

This dataset proposes lists of multi-terms which are characteristic to domains of sciences (ex. 2000 terms about common in embryology research) and the co-occurrence of its items in the literature through time.
Jean-Philippe Cointet, David Chavalarias
core   +2 more sources

A 10-year bibliometric analysis of osteosarcoma and cure from 2010 to 2019

BMC Cancer, 2021
Background In recent decades, the 5-year survival rate of osteosarcoma remains poor, despite the variety of operations, and exploration of drug therapy has become the key to improvement.
Wacili Da, Zhengbo Tao, Yan Meng, Kaicheng Wen, Siming Zhou, Keda Yang, Lin Tao   +6 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source