Results 41 to 50 of about 451,390 (293)

Fracture Propagation Driven by Fluid Outflow from a Low-permeability Aquifer [PDF]

, 2013
Deep saline aquifers are promising geological reservoirs for CO2 sequestration if they do not leak. The absence of leakage is provided by the caprock integrity.
DT Snow, E Detournay, F Cappa, Gennady Yu. Gor, GY Gor, Howard A. Stone, HS Carslaw, J Geertsma, J Smith, J Zhang, Jean H. Prévost, JP Morris, M Iding, M Preisig, O Coussy, P Humez, RH Nilson, S Goodarzi   +17 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

On the Formation of CO2 and Other Interstellar Ices

, 2011
We investigate the formation and evolution of interstellar dust-grain ices under dark-cloud conditions, with a particular emphasis on CO2. We use a three-phase model (gas/surface/mantle) to simulate the coupled gas--grain chemistry, allowing the ...
Garrod, Robin T., Pauly, Tyler
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Pore-scale evaluation of CO2 miscible displacement in porous rocks induced by convection and diffusion: implications for CO2 geo-sequestration

International Journal of Coal Science & Technology
CO2 enhanced oil recovery plays an important role in carbon storage and utilization. However, the incomplete understanding of the underlying microscopic convection–diffusion mechanisms in complex pore structures has constrained the broader industrial ...
Xiangjie Qin, Han Wang, Jinsui Wu, Gang Wang, David A. Wood, Jianchao Cai   +5 more
doaj   +1 more source

Diffusion, mass transfer and oil mobilization mechanisms of CO2 huff-n-puff in Gulong shale oil reservoirs

Petroleum Exploration and Development
To reveal the complex crude oil-CO2 interaction mechanism and oil mobilization behavior during CO2 huff-n-puff in shale-type shale oil reservoirs, CO2 huff-n-puff experiments with on-line nuclear magnetic resonance monitoring were conducted on Gulong ...
Xiao HAN, Zhaojie SONG, Sen DENG, Chenggang XIAN, Binhui LI, Peiyu LI, Yilei SONG, Jiatong JIANG, Bingchen LYU, Lichao ZHANG   +9 more
doaj   +1 more source

Numerical analysis of water-alternating-CO2 flooding for CO2-EOR and storage projects in residual oil zones

International Journal of Coal Science & Technology, 2023
Residual oil zones (ROZs) have high residual oil saturation, which can be produced using CO2 miscible flooding. At the same time, these zones are good candidates for CO2 sequestration.
Boyu Liu, Jun Yao, Tunan Sun
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Responses of leaf stomatal and mesophyll conductance to abiotic stress factors

Journal of Integrative Agriculture, 2022
Plant photosynthesis assimilates CO2 from the atmosphere, and CO2 diffusion efficiency is mainly constrained by stomatal and mesophyll resistance. The stomatal and mesophyll conductance of plants are sensitive to abiotic stress factors, which affect the ...
Sheng-lan LI, Ting-ting TAN, Yuan-fang FAN, Muhammad Ali RAZA, Zhong-lin WANG, Bei-bei WANG, Jia-wei ZHANG, Xian-ming TAN, Ping CHEN, Iram SHAFIQ, Wen-yu YANG, Feng YANG   +11 more
doaj   +1 more source