Results 61 to 70 of about 1,345,233 (308)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Dynamic spatial spillover effects of financial agglomeration on CO2 emissions: the case of China

Humanities & Social Sciences Communications
Research on the impact of financial agglomeration on CO2 emissions is a vital avenue for advancing CO2 emissions reduction and aligning with the Sustainable Development Goals set forth by the United Nations.
Jun Wan, Chenggang Li, Zhangting Yang, Liang Wu, Mu Yue   +4 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

A Structural nonparametric reappraisal of the CO2 emissions-income relationships. [PDF]

Relying on a structural nonparametric estimation, we show that CO2 emissions clearly increase with income at low income levels. For higher income levels, we observe a decreasing relationship, though not significant.
Micheline Goedhuys, Phu Nguyen-Van, Theophile T. Azomahou   +2 more
core  

Explaining and modeling the impacts of inclusive finance on CO2 emissions in China integrated the intermediary role of energy poverty

Humanities & Social Sciences Communications
Inclusive finance has the potential to impact CO2 emissions resulting from energy activities by influencing regional economic behavior. To explore this relationship, this research makes use of panel data covering 30 Chinese provinces between 2004 and ...
Qiong Shen, Rui Wu, Yuxi Pan, Yanchao Feng   +3 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Financial Development, Energy Consumption and CO2 Emissions: Evidence from ARDL Approach for Pakistan [PDF]

The paper explores the existence of a long run equilibrium relationship among CO2 emissions, financial development, economic growth, energy consumption, and population growth in Pakistan.
Faridul, Islam, Muhammad Sabihuddin, Butt, Muhammad, Shahbaz   +2 more
core  

Unequal emissions – unequal policy impacts: how do different areas of CO2 emissions compare? [PDF]

, 2014
Distributional implications of climate change mitigation policies relate to important questions about fairness: which groups bear the highest burdens – or receive the greatest assistance – from these policies and how does this relate to their ...
Buchs, Milena, Schnepf, Sylke V., Bardsley, Nicholas   +2 more
core   +2 more sources

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

Advanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios, Anthony Gonzalez, Aleksander Aleman, Tyler Dolmetsch, Tanaji Paul, Arvind Agarwal   +5 more
wiley   +1 more source

Why have CO2 emissions increased in the transport sector in Asia ? underlying factors and policy options [PDF]

Rapidly increasing emissions of carbon dioxide from the transport sector, particularly in urban areas, is a major challenge to sustainable development in developing countries. This study analyzes the factors responsible for transport sector CO2 emissions
Timilsina, Govinda R., Shrestha, Ashish
core