Results 61 to 70 of about 167,197 (305)

Light-independent regulation of algal photoprotection by CO2 availability

open access: yesNature Communications, 2023
Photosynthetic algae have evolved mechanisms to cope with suboptimal light and CO2 conditions. When light energy exceeds CO2 fixation capacity, Chlamydomonas reinhardtii activates photoprotection, mediated by LHCSR1/3 and PSBS, and the CO2 Concentrating ...
M. Águila Ruiz-Sola   +18 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Microbial autotrophy explains large-scale soil CO2 fixation [PDF]

open access: yes, 2022
12 páginas.- 6 figuras.- 4 referencias.-Microbial communities play critical roles in fixing carbon from the atmosphere and fixing it in the soils. However, the large-scale variations and drivers of these microbial communities remain poorly understood ...
Chen, Wenli   +27 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Maximizing Energy Content and CO2 Bio-fixation Efficiency of an Indigenous Isolated Microalga Parachlorella kessleri HY-6 Through Nutrient Optimization and Water Recycling During Cultivation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
An alternative source of energy and materials with low negative environmental impacts is essential for a sustainable future. Microalgae is a promising candidate in this aspect.
Wasif Farooq, Wasif Farooq
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Nitrogen Isotopes in the Global Ocean [PDF]

open access: yes, 2013
Nitrogen is an essential nutrient for life. Its low abundance throughout much of the sunlit surface ocean limits the growth of primary producers that form the base of ocean ecosystems.
Somes, Christopher J.   +1 more
core  

Remarkable synergistic effect between copper(I) and ionic liquids for promoting chemical fixation of CO2 [PDF]

open access: yes, 2017
Recently, efficient chemical conversion of CO2 into high value chemicals at room temperature and atmospheric pressure without using noble metal catalysts remains a great challenge. In this work, we find that the carboxylative cyclization of propargylic
Zhiyong Li   +15 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Cell-nanoparticle assembly fabricated for CO2 capture and in situ carbon conversion [PDF]

open access: yes, 2016
Some microorganisms can selectively capture carbon dioxide without light irradiation, which proposes a wide application prospect. The purpose of this study was to create a microorganism-nanoparticle assembly, which will be used for carbon dioxide ...
Li, Qiang   +9 more
core   +1 more source

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