Results 41 to 50 of about 465,511 (293)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study

Clinical, Cosmetic and Investigational Dermatology, 2018
Mostafa Kadry,1 Abeer Tawfik,2 Noha Abdallah,2 Ashraf Badawi,2,3 Hisham Shokeir2 1Faculty of Medicine, Dermatology Department, Helwan University Cairo, Helwan, Egypt; 2Dermatology Unit, Department of Medical Applications of Lasers (MAL), National ...
Kadry M, Tawfik A, Abdallah N, Badawi A, Shokeir H   +4 more
doaj  

LDPE Oxidation by CO2 Laser Radiation (10.6 µm)

International Journal of Polymer Science, 2018
Thermooxidation of LDPE films by CO2 laser radiation, 10.6 μm, was characterized by Fourier transform infrared spectroscopy with attenuated total reflectance (FTIR-ATR).
A. Martínez-Romo, R. González-Mota, J. J. Soto-Bernal, I. Rosales-Candelas   +3 more
doaj   +1 more source

QUEILITE ACTÍNICA: ABLAÇÃO COM LASER CO2 VERSUS VERMELHECTOMIA – ANÁLISE DE 11 ANOS

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2014
Introdução: A queilite actínica é uma lesão pré-maligna que ocorre predominantemente no vermilion do lábio inferior de indivíduos do sexo masculino.
Rita Cabral, Vera Teixeira, Ricardo Vieira, Américo Figueiredo   +3 more
doaj   +1 more source

The comparison between microneedling and fractional CO2 laser for amniotic membrane stem cell-conditioned medium and vitamin C in photoaging treatment

Indian Journal of Dermatology, 2023
Context: Photoaging correlates with ultraviolet radiation (UVR). In addition to direct and indirect DNA damage, UVR leads to a breakdown of collagen, resulting in enlarged pores, visible wrinkles, also uneven skin tones and pigmentations.
Diah M Indramaya, Muhammad Y Listiawan, Irmadita Citrashanty, Maylita Sari, Menul A Umborowati, Vidyani Adiningtyas, Dyah A Pitasari, Agatha A Ayu, Fedik A Rantam, Cita R S. Prakoeswa   +9 more
doaj   +1 more source

Stabilization of an AM mode-locked tea CO2 laser [PDF]

, 1983
An increased shot-to-shot reproducibility has been obtained by injection of radiation from a cw CO2 laser in an amplitude mode-locked TEA CO2 laser without additional pulse broadening.
Goor, F.A. van
core   +3 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source