Results 121 to 130 of about 737,629 (313)

Electrocatalytic CO2 Reduction to Formate with Molecular Fe(III) Complexes Containing Pendent Proton Relays

, 2019
Electrocatalytic performance of two Fe complexes for CO2 reduction to formate is described.
Joseph S., Kuehner, Shelby L., Hooe, Asa W., Nichols, Diane A., Dickie, Charles, Machan   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Carbon Dioxide Splitting: A Summary of the Peer-Reviewed Scientific Literature

, 2008
Increasing concentrations of carbon dioxide (CO2) in the atmosphere have stimulated significant global research and development efforts regarding the reduction in CO2 emissions from all point and non-point sources. In addition to technologies that do not
Sierra Rayne
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Organic Chemistry and the Potentials of the Bulk-Reduction of CO2

CHIMIA, 1988
André M. Braun, David G. Skolnick
doaj   +1 more source

Ligand-Centered Electrochemical Processes Enable CO2 Reduction with a Nickel Bis(triazapentadienyl) Complex

, 2018
We report the synthesis of Ni(TAPPy)2 (TAPPy = 1,3,5-triazapentadienyl-2,4-bis(2-pyridyl)) and its reactivity with CO2 under reducing conditions. Electrochemical reduction of Ni(TAPPy)2 under inert gas reveals that the complex accommodates up to two ...
Zachary, Dubrawski, Chase, Radford, Jian-Bin, Li, Roland, Roesler, Alexander, Hyla, Janina, Willkomm, Joshua E., Heidebrecht, Gregory C., Welch, Sathish, Ponnurangam, Demyan E., Prokopchuk, Braulio M., Puerta Lombardi, Warren, Piers   +11 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

CO2 Reduction Characteristics at Pt0.5Ru0.5/C Cathode of H2-CO2 Polymer Electrolyte Fuel Cell

Electrochemistry
CH4 production by CO2 reduction using a membrane electrode assembly containing a Pt/C electrocatalyst was recently demonstrated. Because this CO2 reduction reaction occurs at approximately its theoretical electrode potential, it is possible to generate ...
Shofu MATSUDA, Yuta YOSHIDA, Minoru UMEDA   +2 more
doaj   +1 more source

Amorphous CuSbOx composite-catalyzed electrocatalytic reduction of CO2 to CO: CO2 demand-supply-regulated performance

The path to practical production of targeted chemicals and fuels application via carbon dioxide reduction reactions (CO2RRs) remains a significant challenge mainly due to low CO2 solubility.
White, J, Sun, JW, Wang, Y, Li, WJ, Liu, P, Zhao, H, Yang, HG, Fu, HQ, Lian, C, Yu, T, Wu, Y, Bedford, NM, Rufford, TE   +12 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source