Results 101 to 110 of about 4,382,655 (302)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Electrocarboxylation in supercritical CO2 and CO2-expanded liquids [PDF]

, 2008
In this study, the electrocarboxylation of benzyl chloride in pressurized CO2, or pressurized mixtures of dimethylformamide (DMF) and CO2, was investigated in order to synthesize phenylacetic acid.
Cognet, Patrick, Camy, Séverine, Condoret, Jean-Stéphane, Chanfreau, Sébastien   +3 more
core   +1 more source

Eco-engineered masonry from ferrosilicon slag-incorporated clay bricks for sustainable construction: mechanical robustness, thermal efficiency, and CO2 mitigation

Reviews on Advanced Materials Science
The worldwide demand for sustainable construction materials is rising due to the escalating necessity for energy-efficient structures and environmental preservation.
Kassim Amaged, Tarek Dalia, Ahmed Marwa M., Yousef Ayman, Maafa Ibrahim M., Barakat Nasser A. M., Ragab Ayman   +6 more
doaj   +1 more source

Advances in covalent organic frameworks for photocatalytic CO2 reduction: Strategies and future perspectives

Nano Research Energy
The rapid depletion of fossil fuels and increasing emissions of greenhouse gases, particularly CO2, have amplified global energy and environmental challenges.
Muhammad Kashif Aslam, Iftikhar Hussain, Ali H. Al-Marzouqi, Maowen Xu   +3 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Cu-Based Materials for Enhanced C2+ Product Selectivity in Photo-/Electro-Catalytic CO2 Reduction: Challenges and Prospects

Nano-Micro Letters
Highlights The latest advancements in Cu-based catalysts for photocatalytic and electrocatalytic CO2 reduction into C2+ products are reported. The relationship between the Cu surfaces and their efficiency in photocatalytic and electrocatalytic CO2 ...
Baker Rhimi, Min Zhou, Zaoxue Yan, Xiaoyan Cai, Zhifeng Jiang   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Future atmospheric CO2 leads to delayed autumnal senescence

, 2007
Growing seasons are getting longer, a phenomenon partially explained by increasing global temperatures. Recent reports suggest that a strong correlation exists between warming and advances in spring phenology but that a weaker correlation is evident ...
BIRGIT GIELEN, KATRE KETS, Scarascia-Mugnozza, Giuseppe E., GIUSEPPE E. SCARASCIA-MUGNOZZA, MATTHEW J. TALLIS, Gielen, Birgit, Percy, Kevin E., CHRISTIAN P. GIARDINA, Ket, Katre, BENIAMINO GIOLI, Ketss, Katre, Calfaprieta, Carlo, Calfapietra, Carlo, MARK E. KUBISKE, CARLO CALFAPIETRA, Beniamino, Giolis, Gioli, Beniamino, Kubiske, Mark E., DAVID F. KARNOSKY, Migliettas, Franco, FRANCO MIGLIETTA, Scarascia-Mugnozza, Giuseppe, POOJA S. GUPTA, GAIL TAYLOR, Gupta, Pooja S., KEVIN E. PERCY, Karnosky, David F., Miglietta, Franco, Tallis, Matthew J., STEPHEN P. LONG, Gupta, Poojas S., Long, Stephen P., Kets, Katre, Taylor, Gail, Giardina, Christian P.   +34 more
core   +1 more source