Results 81 to 90 of about 737,629 (313)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Integrating Stamping Tool Temperature Effects into Early-Stage Process Design: Insights from an Industrial Benchmark [PDF]
MATEC Web of ConferencesReducing the CO2 footprint has become a key objective in the manufacturing sector, with the automotive industry being no exception. A significant portion of a car body consists of stamped components, making the reduction of CO2 emissions in stamping ...
Insausti Lide +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Investigating a scaled-up electrolyser for acidic electrochemical CO2 reduction to formic acid [PDF]
, 2023 openIn questo studio è stato indagato il processo di riduzione della CO2 in acido formico in ambiente acido mediante l’utilizzo di appositi elettrolizzatori.
CARLETTO, ALBERTO
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Effects of a Sudden CO2 reduction in Spain [PDF]
Spanish emissions of carbon dioxide have grown by more than 40% in 2004 with respect to 1990. This is not compatible with the EU allocation of Kyoto-mandated CO2 reduction, even taking into account that Spanish emissions are allowed to rise by 15% in ...
Miguel Rodriguez, Xavier Labandeira
core
Graphene Supported Tungsten Carbide as Catalyst for Electrochemical Reduction of CO2
, 2019 Electrochemical reduction of CO2 to useful chemical and fuels in an energy efficient way is currently an expensive and inefficient process. Recently, low-cost transition metal-carbides (TMCs) are proven to exhibit similar electronic structure ...
Sahithi, Ananthaneni, Rees, Rankin
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Hydroxyl-Modified C3N4-Ni Nanosheets Enhance Photocatalytic CO2Methanation
Taiyuan Ligong Daxue xuebao【Purposes】 In photocatalytic CO2 reduction reaction, since the electron transfer efficiencies of CH4 and CO are close and their thermodynamic properties are similar, achieving high electron selectivity for CH4 still faces significant challenges.【Methods】
XIAO Shi +3 more
doaj +1 more source