Results 61 to 70 of about 4,382,655 (302)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Investigation of isothermal unsteady-state CO2 Capture and Reduction over K-promoted supported Cu-catalysts [PDF]

open access: yes, 2022
Nella tesi viene studiato un nuovo processo, denominato CO2 Capture and Reduction. In questo processo catalitico, la CO2 contenuta in correnti diluite, come ad esempio i gas di scarico da post-combustione, può essere catturata grazie ad un catalizzatore
Minorello, Stefano
core  

New experiences with foamed bitumen asphalts in hungarian road building

open access: yesRomanian Journal of Transport Infrastructure, 2015
The use of low temperature (LT) asphalt products can result in a significant decrease of temperature required for asphalt production. This reduces energy costs and consumption.
Puchard Zoltan, Gorgenyi Agnes
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Renewable production of nylon precursors from lignin

open access: yesCell Reports Sustainability
Summary: Cyclohexanone and cyclohexanol are critical monomeric precursors in the production of nylon 6 and nylon 66, which are conventionally sourced from petroleum.
Kaile Li   +9 more
doaj   +1 more source

Photoelectrocatalytic CO2 reduction

open access: yes, 2023
Reuse or conversion of CO2 using economical and simple methods is one of the greatest challenges of this century. The present work aims to show how photoelectrocatalysis has gained attention in this field. A critical analysis is carried out identifying the best materials able to promote the conversion of CO2 to products with higher added value like ...
Brito, Juliana Ferreira de   +2 more
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Electrochemical Reduction of CO2 by SnS⎸PTFE⎸Pt Surface in an Aqueous Imidazole Medium: Catalysis and Kinetics [PDF]

open access: yes
Development of a novel SnS⎸PTFE⎸Pt electrode as an efficient catalyst for electrochemical CO2 reduction to formate in aqueous alkaline imidazole medium is reported in this paper.
Islam, Md. Tarikul   +7 more
core   +1 more source

Multiscale investigation of cavitation surge characteristics in the swirling flow using Eulerian-Lagrangian method

open access: yesUltrasonics Sonochemistry
Hydrodynamic cavitation (HC) surge accompanied by strong swirl is widely present in fluid machinery and has become a hot topic in many engineering fields. This paper employed a two-way coupling Eulerian-Lagrangian multiscale cavitation modeling method to
Ziyang Wang   +3 more
doaj   +1 more source

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