Results 41 to 50 of about 221,665 (265)
Diyala Journal of Engineering Sciences, 2018 The process modeling and optimization of carbon dioxide (CO2) separation from carbon dioxide-methane (CH4) binary gas mixture through hydrotalcite (HT)-silica membrane using statistical design of experiments (DoE) is reported in this study.
Ahmed Daham Wiheeb
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Energy Science & Engineering, 2023 With climate change concerns on the rise, finding efficient and sustainable ways to separate carbon dioxide from industrial gas mixtures has become increasingly important. Membrane‐based gas separation technologies offer a promising solution due to their
Ali Majnoon +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Application of membrane technology for separation CO2 from natural gas [PDF]
Podzemni Radovi, 2020 Natural gas consists of a mixture of hydrocarbons with the largest share of methane, and non-hydrocarbon impure components such as N2, CO2 and H2S. In order to fulfill the gas market requirements, it is necessary to separate these unwanted components ...
Tomić Lola +4 more
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
HYDROGEN PURIFICATION USING A MICROPOROUS HYDROTALCITE-SILICA COMPOSITE MEMBRANE
Diyala Journal of Engineering Sciences, 2015 A novel thin microporous composite membrane of a dual-element hydrotalcite-silica was prepared on porous alumina support by sol-gel method. Strong CO2 adsorption on hydrotalcite material inhibited the diffusion of H2 through the membrane and decreased ...
Ahmed Daham Wiheeb
doaj