Results 131 to 140 of about 119,814,942 (292)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

General catalogue of illuminating glassware and lighting fixtures for commercial and residential lighting / manufactured by The Crown Crystal Glass Co.

open access: yes, 1920
Cover title: Lighting ware by Crown Crystal Glass Co.; Electronic reproduction. Canberra, A.C.T.
Crown Crystal Glass Co.
core  

N°2, Kurverein B. Silvaplana, Hofer & Co. A.G., Zürich

open access: yes
N°2, KURVEREIN B. SILVAPLANA, HOFER & CO. A.G., ZÜRICH N°2, Kurverein B. Silvaplana, Hofer & Co. A.G., Zürich ( -
Hofer & Co. A.G., Zürich
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Invasive CO 2 monitoring with arterial line compared to end tidal CO 2 during peroral endoscopic myotomy. [PDF]

open access: yesEndosc Int Open, 2023
Duarte-Chavez R   +7 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ireland [cartographic material]

open access: yes
Map of Ireland showing the names and boundaries of counties and other administrative areas such as cities and boroughs.The map also shows types of roads and watercourses.; Prime meridian: Greenwich.; Plate [2] from: Improved edition of the new British ...
Henry Teesdale & Co.
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