Results 141 to 150 of about 119,814,942 (292)
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The 1841 Pigot & Co.'s directory of York, Leicester & Rutland, Lincoln, Northampton and Nottingham, and includes ...
Pigot & Co. historical directories;
core
Curing of Poly(styrene-co-methyl methacrylate-co-2-hydroxyethyl methacrylate) Terpolymers in the Presence of Amino Compounds of Different Structures. [PDF]
Pugacheva TA +8 more
europepmc +1 more source
Design of Dot-matrix Drawing Software Used in Mine LED Electronic Display Board
For problems of inaccurate drawing and poor visibility of mine LED electronic display board using vector technical to draw graphics, the paper proposed a design scheme of dot-matrix drawing software which can be applied in different types of electronic ...
DING Rui-qi +5 more
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Sales plan for land in Glenormiston, Victoria. Includes locality plan.; "Vendors: The Land Co. of Australasia, Ltd."; "Robert Allan, surveyor, Ballarat."; "Solicitors: Messrs. Cuthbert, Hamilton, & Wynne, Collins Street, Melbourne."; Also available in an
Fisken, Valentine & Co.
core
Toward a CO$_{2}$-neutral biotechnology : itaconate production using CO$_{2}$ derived co-substrates
Today’s (chemical) industry is founded on fossil-based raw materials (i.e., coal, gas, and oil), despite their negative impacts on our all future, including global warming. A change from fossil to sustainable raw materials is required since the demand for food, energy, and chemicals will keep increasing for the next decades.
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

