Results 91 to 100 of about 1,910,873 (246)

Exploring the diversity of three Northern Atlantic sea beet populations

open access: yesFrontiers in Plant Science
Sea beet [Beta vulgaris ssp. maritima (L.) Arcang.] populations exhibit high genetic diversity and possess valuable traits that could enhance resilience, disease resistance, and tolerance to abiotic stress. In contrast, the genetic variation in the sugar
Lisa Bertram   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diethanolamine Complexes of Co(II), Ni(II), Zn(II) and Cd(II)

open access: yes, 1980
Department of Chemistry, Ravenshaw College, Cuttaek-753 003 Manuscript received 8 August 1979, accepted 30 November 1979 Complexes of diethanolamine of the composition [ML2]X2 or [ML2X2] have been synthesised where M = Co(Il), Ni(II), Cd(II) and X= Cl-, Br-, NO2-, NCS- and ClO-4.
A. SAMANTRAY   +2 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Stark Broadening of Heavy Element Spectral Lines in Hot Stars: Au II, Co II, Ti II and Co III

open access: yesOpen Astronomy, 2000
Tankosić D.   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Analysis of Organizational Factors Promoting Data Utilization in Large Japanese Corporations

open access: yesMaketingu rebyu
The objective of this study is to identify the activities required to achieve effective outcomes in data utilization within large Japanese corporations. Building upon research on Big Data Analytics Capabilities, as represented by Gupta and George (2016),
Kazuo Yagura
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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