Simultaneous Derivative Spectrophotometric Determination of Co(II), Cu(II) and Fe(II)
Aşçi, Β. +2 more
doaj +1 more source
Solvatochromic, spectroscopic, DFT calculations, antimicrobial and docking studies of new Fe(III), Co(II), and Ni(II) chelates containing 1,2,4-triazine. [PDF]
Abdelrhman EM +5 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Preparation of Hierarchically Structured Perlite NPs/Metformin-Co (II) System to Catalyze the Green Synthesis of Pyrazolopyranopyrimidines. [PDF]
Shurbakhlu JR, Moradi L, Dehghani A.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Enantioselective Radical Dearomative Conjugate Amination Enabled by Co(II)-Based Metalloradical Catalysis. [PDF]
Xu P, Wang DS, Zhu Z, Zhang XP.
europepmc +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Novel amide-based macrocyclic Co(ii) complexes: correlating structural, computational, and biological properties through DFT and docking. [PDF]
Subhash +4 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Observation of spin-crossover behaviour in Co(ii)-terpyridine complexes possessing π-conjugated substations. [PDF]
Soejima K +6 more
europepmc +1 more source

