Results 101 to 110 of about 838,800 (309)

Enhancing physical fitness in older adults: a six-month medium intensity training intervention yields significant improvements

open access: yesBMC Sports Science, Medicine and Rehabilitation
Background Maintaining physical fitness in older adults is crucial for preventing functional decline. This study aimed to examine the effects of a 6-month medium-intensity training (MIT) programme on physical fitness components in older adults.
Rahmat Hidayat   +3 more
doaj   +1 more source

DISEÑO Y VALIDACIÓN DE UN CUESTIONARIO PARA ESTUDIAR EL PROCESO DE FORMACIÓN DE LOS FUTBOLISTAS [Design and validation of a questionnaire to study the process of training football players]

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2020
Resumen El objetivo de este estudio fue diseñar y validar un cuestionario a través de un análisis cuantitativo y cualitativo, con la finalidad de obtener una herramienta que ayude a conocer mejor el proceso de formación de los jugadores y jugadoras de ...
Alberto Martín Barrero   +2 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Modelo Relacional Integral para la Gobernanza: Gaztedi 2030

open access: yesGIGAPP Estudios Working Papers, 2019
El Modelo Relacional GAZTEDI de la Diputación Foral de Bizkaia persigue modernizar la Administración Pública según los nuevos y exigentes criterios de eficiencia y coherencia en la gestión pública, transparencia, rendición de cuentas y participación ...
Estibaliz Biguri, Danel Alberdi
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

THE PRIMORDIAL QUALITIES OF THE COACH WHICH INITIATES AND PREPARES ATHLETES WHO PARTICIPATE IN COMBAT SPORTS (gr-rom fights, free fights, judo, karate) [PDF]

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2018
Coaching profession requires a lot of passion and devotement, since it requires a large amount of physical and mental work , and many sacrifices. A coach 's first a teacher patiently embracing a bit of his knowledge in future performers , then he is ...
Lazăr Tipa, Răduțescu I. Ion
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

ORIENTACIÓN DE LOS ENTRENADORES DE BALONMANO. INFLUENCIA DEL GÉNERO, EDAD, EXPERIENCIA, FORMACIÓN Y DEDICACIÓN SEMANAL [Handball coaches’ orientation. Influence of gender, age, experience, federative level and weekly training hours]

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2018
La conducta que adopte el entrenador deportivo facilitará o perjudicará el grado de satisfacción, motivación, implicación y compromiso hacia la práctica deportiva, influyendo por lo tanto en su adherencia deportiva.
Manuel Gómez López   +2 more
doaj   +2 more sources

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