Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen +4 more
wiley +1 more source
Bacterial biofilms with emphasis on coagulase-negative staphylococci
In addition to their capacity to attach to surfaces, various groups of microorganisms also produce an extracellular polymeric substance known as "slime". This slime forms a thin layer around cells known as biofilm.
A Oliveira, MLRS Cunha
doaj +1 more source
Mechanisms of linezolid resistance among coagulase-negative staphylococci determined by whole-genome sequencing. [PDF]
UnlabelledLinezolid resistance is uncommon among staphylococci, but approximately 2% of clinical isolates of coagulase-negative staphylococci (CoNS) may exhibit resistance to linezolid (MIC, ≥8 µg/ml).
Bobenchik, April +7 more
core +2 more sources
ABSTRACT Catheter‐associated urinary tract infections (CAUTI) are a common healthcare‐associated infection in children and a major contributor to increased morbidity, prolonged hospital stays and higher healthcare costs. This narrative review uses an evidence‐informed approach highlighting recent paediatric literature (2000–2025) to provide an overview
Simon P. Paget +4 more
wiley +1 more source
Mortality in intensive care: The impact of bacteremia and the utility of systemic inflammatory response syndrome [PDF]
Background: The purpose of this study was to determine the impact of bacteremia on intensive care unit (ICU) mortality and to develop a bacteremia prediction tool using systemic inflammatory response syndrome (SIRS) criteria. Methods: Patients
Booth, Malcolm G. +4 more
core +1 more source
Multidrug resistance of bacterial pathogens in canine pyometra
Objectives To characterise multidrug antimicrobial resistance and pathogenicity profiles of bacteria isolated from different anatomical sites in bitches with pyometra, emphasising their clinical relevance for diagnosis and therapeutic decision‐making in small animal practice.
M. G. M. Camozzi +7 more
wiley +1 more source
tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA [PDF]
A real-time nucleic acid sequence-based amplification assay, targeting tmRNA, was designed for the rapid identification of Staphylococcus aureus. The selectivity of the assay was confirmed against a panel of 76 Staphylococcus strains and species and 22 ...
Anonymous +9 more
core +1 more source
Impact of Dental Status on Heart Transplantation Outcomes
ABSTRACT Objective Oral infections and poor dental health may contribute to systemic complications after heart transplantation, yet data on their impact is limited. In the absence of standardized dental guidelines for transplant candidates, this study evaluated preoperative dental status and its association with post‐transplant outcomes.
Katharina Theresa Obermeier +8 more
wiley +1 more source
Serum procalcitonin for discrimination of blood contamination from bloodstream infection due to coagulase-negative staphylococci [PDF]
The diagnostic value of serum procalcitonin (PCT) to distinguish blood contamination from bloodstream infection (BSI) due to coagulase-negative staphylococci was evaluated.
Mueller, B., Schuetz, P., Trampuz, A.
core +1 more source
I commend the authors on their efforts in developing a strong manuscript centered around an important topic, the trajectory of health‐related quality of life following PJI. Their statistical analyses have been significantly improved, and their findings are both novel and clinically relevant. Their discussion is succinct, thorough, and readable.
Lena Schwake +5 more
wiley +1 more source

