Results 101 to 110 of about 25,876 (209)

Adding Bortezomib and Bendamustine to High‐Dose Melphalan in Autologous Haematopoietic Stem Cell Transplantation for Relapsed Multiple Myeloma—A Single Centre Retrospective Study

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction High‐dose melphalan (HDM) followed by autologous haematopoietic stem cell transplantation (ASCT) remains the standard of care for eligible patients with multiple myeloma (MM). Our objective was to evaluate the effectiveness and safety of adding bortezomib and bendamustine to melphalan (BBM) compared with HDM for relapsed MM, and ...
Thomas Silfverberg   +3 more
wiley   +1 more source

Lower synovial leucocyte count and polymorphonuclear percentage reliably differentiate periprosthetic joint infection after unicompartmental knee arthroplasty

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 4, Page 1310-1317, April 2026.
Abstract Purpose This study aimed to determine diagnostic thresholds for synovial fluid leucocyte count and polymorphonuclear (PMN) percentage to identify the diagnosis periprosthetic joint infection (PJI) in patients with failed unicompartmental knee arthroplasties (UKAs).
Stefanie Donner   +7 more
wiley   +1 more source

A Pilot Metagenomic Study Demonstrating Virtual Reality Head Mounted Displays Utilized in Medical Education Are Reservoirs of Viable Pathogenic Microbes

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Metagenomic analysis identified 27 pathogenic bacteria including 4 "ESKAPE" pathogens (Enterobacter sp., Staphylococcus aureus, Klebsiella spp., and Escherichia coli) and numerous organisms associated with ocular infections. A broad range of antimicrobial resistance genes were identified conveying resistance to Methicillin, Aminoglycosides, Macrolides,
Adrian Goldsworthy   +8 more
wiley   +1 more source

Of Commensals and Opportunists: Genomics of Coagulase‐Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
The genomes of coagulase‐negative staphylococci (CoNS) isolated during sequential ear and eye infections in a healthy adult are analyzed. We highlight the identification of a community‐acquired S. capitis subsp. urealyticus ST1 lineage carrying a mosaic SCCmec IV element, linking common skin commensals to multidrug‐resistant strains associated with ...
Soo Sum Lean   +6 more
wiley   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu   +60 more
wiley   +1 more source

Aortic Valve Endocarditis Caused by Streptococcus acidominimus Following Community‐Acquired Pneumonia in a Patient With Diabetes Mellitus: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
Infective endocarditis due to Streptococcus acidominimus is exceedingly rare and poses diagnostic and therapeutic challenges. We present a case that highlights the clinical significance of this uncommon pathogen in a patient with diabetes mellitus who was initially presumed to have community‐acquired pneumonia.
Menghak Heng   +14 more
wiley   +1 more source

One Health Surveillance of Antimicrobial Resistance in the Eastern Mediterranean: The Blackchin Guitarfish as a Case Study

open access: yesGeoHealth, Volume 10, Issue 4, April 2026.
Abstract Antimicrobial resistance (AMR) poses a global One Health challenge, linking human, animal, and environmental health. Marine environments and organisms are increasingly recognized as reservoirs of antimicrobial‐resistant bacteria and mobile genetic elements.
J. Lellouche   +8 more
wiley   +1 more source

Staphylococcal mastitis in dairy cows

open access: yesFrontiers in Veterinary Science
Bovine mastitis is one of the most common diseases of dairy cattle. Even though different infectious microorganisms and mechanical injury can cause mastitis, bacteria are the most common cause of mastitis in dairy cows.
Oudessa Kerro Dego   +2 more
doaj   +1 more source

Plasma calprotectin to assess susceptibility to bloodstream infections during paediatric acute lymphoblastic leukaemia induction treatment

open access: yesBritish Journal of Haematology, Volume 208, Issue 4, Page 1339-1346, April 2026.
Summary Chemotherapy‐induced neutropenia, monitored by peripheral blood absolute neutrophil count (ANC), increases the risk of bloodstream infections (BSIs). However, ANC may not reflect the total neutrophil population, as it omits neutrophils at extravascular sites.
Johanna Vævest Nymann Eriksen   +9 more
wiley   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

open access: yesDiabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli   +8 more
wiley   +1 more source

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