Results 121 to 130 of about 117,766 (329)

Severe bleeding disorders in children with normal coagulation screening tests [PDF]

, 1982
P J Darbyshire, O. B. Eden
openalex   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Advanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge, Fangqin Fu, Yu Gao, Tianchang He, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +7 more
wiley   +1 more source

The role of IL-6 for predicting neonatal sepsis: A systematic review and meta-analysis [PDF]

, 2011
Objective: Neonatal sepsis (NS) is a common and life-threatening disorder in infants. Previous studies showed that interleukin-6 (IL-6) may be a valid non-invasive and rapid method for diagnosis of NS.
Ahani, A., Keshtkar, A., Mirfazeli, A., Roshandel, G., Shahkar, L.   +4 more
core   +1 more source

Central venous access devices in children with congenital coagulation disorders: complications and long‐term outcome [PDF]

, 2000
Corrina McMahon, Jude Smith, Kate Khair, Ri Liesner, Ian Hann, Owen Smith   +5 more
openalex   +1 more source

Corticosterone Contributes to Context‐Triggered Retrieval of Morphine Withdrawal Memories by Acting on Basolateral Amygdala Neurons Projecting to Nucleus Accumbens Core

Advanced Science, EarlyView.
Context associated with morphine withdrawal elicits an increase in serum corticosterone levels. Corticosterone participates in CTR‐MWM by acting on MR, but not GR, in the BLA. MR in BLA→NAcC neurons mediates CTR‐MWM. MR increases presynaptic glutamate release and meanwhile participates in D1 receptor‐induced increases in presynaptic glutamate release ...
Zixuan Cao, Yaxian Wen, Yuanqi Chen, Yali Fu, Hao Yang, Chenshan Chu, Xinli Guo, Yu Yuan, Chao Lei, Huan Sheng, Da Shao, Li Yang, Dongyang Cui, Ming Chen, Bin Lai, Ping Zheng   +15 more
wiley   +1 more source

Plasma tissue factor as a promising marker in multiple sclerosis: Evidence from a two-sample Mendelian randomization study

Translational Neuroscience
Multiple sclerosis (MS) is a major demyelinating disorder that affects the central nervous system. A growing body of evidence has revealed the involvement of coagulation pathway in the pathogenesis of MS.
Pan Rui, Wang Aiqi, Li Yaqi, Xie Qizhi, Lin Meihua, Li Jiayi, Shi Xiaolei   +6 more
doaj   +1 more source

Relationship between coagulopathy score and ICU mortality: Analysis of the MIMIC-IV database

Heliyon
Objective: Coagulopathy score has been applied as a new prognostic indicator for sepsis, heart failure and acute respiratory failure. However, its ability to forecast intensive care unit (ICU) mortality in patients with an acute cerebral hemorrhage (ICH)
Zhijie Xie, Suijun Zhu, Jun Wang, Min Zhang, Xuan Lv, Yijun Ma, Hua Shan, Yinjun Zhong   +7 more
doaj   +1 more source

HIV-associated multi-centric Castleman’s disease with multiple organ failure: cuccessful treatment with rituximab [PDF]

, 2010
Introduction: Multicentric Castleman's Disease (MCD), a lymphoproliferative disorder associated with Human Herpes Virus-8 (HHV-8) infection, is increasing in incidence amongst HIV patients.
Agarwal, B, Cleverley, JR, Cwynarski, K, Doyle, T, Isaacson, PG, Johns, RH, Lipman, M, Shaw, S   +7 more
core  

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

Advanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su, Yang Wang, Xifeng Qin, Yaqiong Xiao, Boshu Ouyang, Lina Hu, Lin Kang, Ruizhe Xu, Ce Xu, Zanya Sun, Chenyu Sun, Huishu Guo, Zhiqing Pang, Shun Shen   +13 more
wiley   +1 more source