Results 221 to 230 of about 3,265,974 (326)

Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic [PDF]

open access: bronze, 2020
Miguel Fernando García‐Gil   +6 more
openalex   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Coagulation Disorder following Red Clover (Trifolium Pratense) Misuse: a Case Report. [PDF]

open access: yesAdv J Emerg Med, 2018
Karimpour-Reihan S   +3 more
europepmc   +1 more source

Cefazolin and Coagulation Disorder: A case report and review of literature

open access: diamond, 2012
Nadeem Ahmed Shaikh   +6 more
openalex   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

open access: yesAdvanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang   +6 more
wiley   +1 more source

Factor X Friuli Coagulation Disorder: Almost 50 Years Later. [PDF]

open access: yesClin Appl Thromb Hemost, 2018
Girolami A   +5 more
europepmc   +1 more source

Advances in Hygroscopic Polymer Gels toward Efficient Atmospheric Moisture Capture and Management

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the research progress of hygroscopic polymer gels (HPGs) in the field of atmospheric moisture management, summarizes their hygroscopic mechanisms, construction strategies, and typical multi‐field applications, highlights the urgency of developing moisture‐adaptive HPGs for low‐humidity arid regions, and ...
Ruofan Zhou   +4 more
wiley   +1 more source

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