Results 41 to 50 of about 111,064 (345)
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Acquired disorders of coagulation
Medicine, 2013 Normal coagulation is a balance between pro- and anti-thrombotic mechanisms. Haemorrhage occurs when factors that promote thrombus formation are dysfunctional/absent and may be due to inherited or acquired factors. The most common acquired abnormalities seen in the clinical setting are covered in this article including vitamin K deficiency and warfarin
openaire +2 more sources
Liver‐specific lncRNAs associated with liver cancers
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina +3 more
wiley +1 more source
Combined Factor VII and X Deficiency [PDF]
, 2011 Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Arora, Sunita +2 more
core
Successful treatment of refractory gastrointestinal bleeding by systemic (oral) ankaferd blood stopper in a patient with Glanzmann thrombasthenia [PDF]
, 2015 Background: Glanzmann Thrombasthenia (GT) is a genetic platelet dysfunction and a life threatening disease. Ankaferd Blood Stopper (ABS) is a topical hemostatic agent of herbal origin which has been recently made available for clinical use.
Doğu, Mehmet Hilmi +3 more
core +2 more sources
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro +12 more
wiley +1 more source
Congenital Factor VII Deficiency Presenting with Isolated Recurrent Hematuria: A Case Report
Acta Medica Iranica, 2021 Introduction: Factor VII deficiency is a rare congenital coagulopathy disorder. In most cases this disorder is diagnosed in childhood. Common symptoms of congenital factor VII deficiency are different and consist of mucosal cutaneous hemorrhage ...
Shahla Ansary Damavandi +3 more
doaj +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Вопросы современной педиатрии, 2012 Treatment of patients with congenital combined coagulation disorder and thrombohemorrhagic syndrome is associated with a number of difficulties, one of them is need of permanent vascular access in order to provide appropriate pathogenetic therapy.
I. N. Nurmeev, L. F. Rashitov
doaj +1 more source
Role of heparanase in ARDS through autophagy and exosome pathway (review)
Frontiers in Pharmacology, 2023 Acute respiratory distress syndrome (ARDS) is the most common respiratory disease in ICU. Although there are many treatment and support methods, the mortality rate is still high.
Fei Feng +5 more
doaj +1 more source