Results 51 to 60 of about 3,265,974 (326)

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Legg-Calvé-Perthes disease and the risk of injuries requiring hospitalization [PDF]

, 2012
Background and purpose Previous studies have suggested that Legg-Calvé-Perthes disease (LCPD) is associated with repetitive trauma, coagulation problems and anatomical abnormalities of the blood supply to the femoral head. The hypothesis that repetitive
Bahmanyar, S., Ekbom, A., Hailer, Y.D., Montgomery, S., Nilsson, O.   +4 more
core   +1 more source

Liquid Crystal Elastomers Under Confinement: A Review of Template‐Based Fabrication and Applications

Advanced Engineering Materials, EarlyView.
Template‐assisted confinement offers powerful ways to control the alignment, structure, and function of liquid crystal elastomers. This review highlights several templating strategies and details how geometry and interfaces shape material responses.
Meng Zhang, Le Yang, Xinyi Ding, James Phillip Scarbrough, Tushar Narayan Singh, Yuxing Yao, Shucong Li, Xiaoguang Wang   +7 more
wiley   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

THE PROBLEM OF PERMANENT VASCULAR ACCESS IN PATIENTS WITH CONGENITAL COMBINED COAGULATION DISORDER AND THROMBOHEMORRHAGIC SYNDROME (A CLINICAL CASE)

Вопросы современной педиатрии, 2012
Treatment of patients with congenital combined coagulation disorder and thrombohemorrhagic syndrome is associated with a number of difficulties, one of them is need of permanent vascular access in order to provide appropriate pathogenetic therapy.
I. N. Nurmeev, L. F. Rashitov
doaj   +1 more source

Degeneracy Algorithm for Random Magnets

, 1998
It has been known for a long time that the ground state problem of random magnets, e.g. random field Ising model (RFIM), can be mapped onto the max-flow/min-cut problem of transportation networks.
A. A. Middleton, A. Hartmann, A. T. Ogielski, A. V. Goldberg, A. V. Goldberg, C. Moukarzel, D. Stauffer, F. Barahona, H. Rieger, J. C. Anglès d’Auriac, J. H. van Lint, J. S. Provan, K. Binder, L. R. Ford, Jr., M. J. Alava, M. O. Ball, M. R. Swift, S. Bastea, S. Bastea   +18 more
core   +2 more sources

Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]

, 2017
The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul, Gomez-Pinilla, Fernando, Meng, Qingying, Yang, Xia, Ying, Zhe, Zhuang, Yumei   +5 more
core   +2 more sources

Viral-Induced Inflammatory Coagulation Disorders: Preparing for Another Epidemic

Thrombosis and Haemostasis, 2021
Several viral infectious diseases have emerged or re-emerged from wildlife vectors that have generated serious threats to global health. Increased international travel and commerce increase the risk of transmission of viral or other infectious diseases ...
T. Iba, J. Levy, M. Levi
semanticscholar   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Bleeding disorders in dental practice: A diagnostic overview

Journal of International Clinical Dental Research Organization, 2014
Dental health care workers are increasingly called upon to provide quality dental care to individuals whose bleeding and clotting mechanisms have been altered by inherited or acquired diseases.
Abhirup Goswami, Amitava Bora, Gautam Kumar Kundu, Samiran Ghosh, Anupam Goswami   +4 more
doaj   +1 more source