Results 191 to 200 of about 189,811 (255)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic. [PDF]

Nat Commun
Whittaker C, Barnsley G, Mesa DO, Cox V, Laydon DJ, Tan CW, Zhu F, Johnson R, Doohan P, Whittles LK, Nedjati-Gilani G, Winskill P, Hogan AB, Deol A, Mukandavire C, Hauck K, Lye DCB, Wang LF, Watson OJ, Ghani AC.   +19 more
europepmc   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Development of a Patient-Centered Outcome Tool for Blepharospasm: A Stepwise Modified Delphi Study. [PDF]

Toxins (Basel)
Berman BD, Qeadan F, Henderson AD, Harrison AR, Defazio G, Hallett M, Kilic-Berkmen G, Wright L, Pentecost S, Reyes P, Tingin A, Jankovic J, Boyd J, Hudgins C, Hieshetter J, Perlmutter JS, Jinnah HA, Pirio Richardson S.   +17 more
europepmc   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

DP-AMF: Depth-Prior-Guided Adaptive Multi-Modal and Global-Local Fusion for Single-View 3D Reconstruction. [PDF]

J Imaging
Zhang L, Xie C, Kitahara I.
europepmc   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Sustainable operation of multi-energy systems under cooperative and non-cooperative strategies. [PDF]

Sci Rep
Karimi H.
europepmc   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

Strengthening Collaboration Between Community-Based Organizations, State Title V Agencies, and Funders by Uplifting Community-Rooted Evidence: A Qualitative Research Study. [PDF]

Matern Child Health J
Powis L, Alvarez ES, Krisowaty L, Kuo O, Vasquez NI, Callejas LM, Burns R, Gore S, Whitner S, Charles C, Taylor-Schiro E.   +10 more
europepmc   +1 more source