Results 201 to 210 of about 13,606 (265)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Strengthening community voices: implementing Local Health Equity Action Teams (LHEATs) to address health disparities. [PDF]

Arch Public Health
Pacheco CM, Bridges K, Ablah E, Collie-Akers V, Ellerbeck E, Morrow E, Honn A, Long N, Love J, Carrillo Martinez C, Knapp K, Miras Neira T, Scott A, Finocchario Kessler S.   +13 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Towards an international research agenda for public health advocacy: Practice, preparedness and knowledge gaps. [PDF]

PLOS Glob Public Health
Cullerton K, D'cunha K, Clifford Astbury C, Hunt D, Bhatti AJ, Aryeetey R.   +5 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

System dynamics modeling in support of community-based decision-making to reduce opioid overdose fatalities. [PDF]

Front Public Health
Canty T, Lootens MR, Sabounchi NS, Thompson RL, Ganguly A, Dsouza N, Kilburn S, Beloch J, Hirsch G, Huang TT, El-Bassel N, Lounsbury DW.   +11 more
europepmc   +1 more source

Diplomatic monocultures in public health diplomacy: a narrative review on conference equity, participation and visibility. [PDF]

Public Health Rev
Ernst M, Münter L, Skali A, Turk E.
europepmc   +1 more source

Addressing Structural Factors to Prevent Youth Violence Through a Multisector Collaborative Approach. [PDF]

Prev Sci
Thompson VM, Watson-Thompson J, Bernard DL, Bah L.   +3 more
europepmc   +1 more source

The impact of the communities that HEAL intervention on the provision of jail-based medication for opioid use disorder & linkage programs at release: Results from a randomized, wait-list controlled trial. [PDF]

J Subst Use Addict Treat
Oser CB, Sprunger JG, Hunt T, Holloway J, Chandler RK, Freisthler B, Balvanz P, Henry BF, Glasgow L, Harris DR, Walsh SL, Aldridge AP, Asman K, Blevins D, Booty MD, Fox AD, Springer SA, Kinnard EN, Knott C, LeBaron PA, Levin FR, Marks KR, McGladrey ML, Nunes EV, Oga EA, Smith MR, Smith MS, Staton M, Stevens-Watkins D, Surratt HL, Walters ST, Zarkin GA, Friedmann PD.   +32 more
europepmc   +1 more source

The role of subtalar extrarticular screw arthroereisis (SESA) in surgical treatment of tarsal coalitions. [PDF]

J Orthop Traumatol
De Pellegrin M, Marcucci L, Guindani N, Brogioni L, Fracassetti D.   +4 more
europepmc   +1 more source