Results 81 to 90 of about 54,357 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Technology Spillovers and Stability of International Climate Coalitions [PDF]
Cooperation in international environmental agreements appears difficult to attain because of strong free-riding incentives. This paper explores how different technology spillover mechanisms among regions can influence the incentive structures to join and
Miyuki Nagashima, Rob Dellink
core
Background and Purpose: Partnerships are a key mechanism in the planning, delivery and management of urban forestry (UF) and green infrastructure (GI). They can facilitate locally rooted co-management and polycentric governance.
Ralph Hansmann +9 more
doaj +1 more source
Introduction to coalitions in graphs
A coalition in a graph consists of two disjoint sets of vertices V1 and V2, neither of which is a dominating set but whose union is a dominating set. A coalition partition in a graph G of order is a vertex partition such that every set Vi of π either is ...
Teresa W. Haynes +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Building Coalitions: Coalition Functioning
This document is FY495, Part 3 of the 16 part series adapted for use in Florida by Elizabeth B. Bolton and Lisa Guion. Reprinted with permission March, 1997. Revised April, 2002.
Charles H. Bell +3 more
openaire +5 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
On the Formation of Coalitions to Provide Public Goods - Experimental Evidence from the Lab [PDF]
The provision of public goods often relies on voluntary contributions and cooperation. While most of the experimental literature focuses on individual contributions, many real-world problems involve the formation of institutions among subgroups ...
Bodo Sturm +2 more
core +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

