Results 91 to 100 of about 282,585 (335)

Molecular studies on the sweet potato virus disease and its two causal agents [PDF]

, 2002
The studies presented in this thesis contribute to an increased understanding of the molecular aspects, variability and interaction of the two most important viral pathogens of sweet potato (Ipomoea batatas L): Sweet potato feathery mottle virus (SPFMV ...
Kreuze, Jan
core  

Antimicrobial peptides: agents of border protection for companion animals. [PDF]

, 2012
Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K, Bevins, Charles L, Leonard, Brian C   +2 more
core   +1 more source

Skin proteomic screening and functional analysis of differential proteins associated with coat color in sheep () [PDF]

Animal Bioscience
Objective Coat color is an important characteristic and economic trait in domestic sheep. In this study, we explored the potential mechanisms and the signaling pathways involved in coat color regulation for sheep.
Zhihong Yin, Shitong Hao, Yuanyuan Zhao, Jinglong Li, Yunli Cui, Yaming Ge, Quanhai Pang   +6 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation [PDF]

, 2018
Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments.
A Talenti, A Yurchenko, A Zrhidri, AGT Pereira, AK Lindholm-Perry, AR Boyko, AS Wilkins, B Cannon, B Dorshorst, B Grisart, B Haase, B Loureiro, B Loureiro, B Loureiro, BG Oliver, BS Weir, CB Kaelin, D Boruszewska, D Wright, D Yang, DR Schrider, EA Ostrander, EM Ibeagha-Awemu, F Li, F Schlamp, F Tajima, FB Axelrod, G Valverde, H Li, H Li, H Mannen, H Pausch, H Yamada, H Zhang, HD Daetwyler, HD Daetwyler, HP Jedema, I Kurth, I Mathieson, I Naka, I Urbinati, J Kim, J Martin-Tereso, J Queiros, JD Jensen, JD Storey, JE Decker, JJ Simoni Gouveia de, JK Pickrell, K Kim, K Konczol, K Soini, K Wimmers, KC Wollenberg Valero, KE Lotterhos, L Ma, LA Raven, M Cohen-Zinder, M Knoll, M Nei, M Nizon, M Saatchi, MI Fariello, MJ Emmett, MN Weedon, MR Upadhyay, MRS Fortes, NA Mandal, O Delaneau, O Tange, P Danecek, P Scheet, Q Qiu, QL Meng, R Verity, R Weikard, R Xiang, RL Minster, RR Mota, S Boitard, S Bolormaa, S Bongiorni, S Fan, S Makvandi-Nejad, S Moon, S Purcell, S Roth, S Roy, S Sasaki, S Wu, SD Berry, SH Carroll, SJ Yue, SR Grossman, T Iso-Touru, T Nishimaki, TY Yeh, W Barendse, X Zheng, X Zheng, XL Wang, Y Gao, Y Gao, Y Liu, Y Ma, Y Qin, Y Wang, YT Utsunomiya, Z Gu   +108 more
core   +4 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

P1 of strawberry vein banding virus, a multilocalized protein, functions as a movement protein and interacts with the coat protein

Journal of Integrative Agriculture, 2022
Although the complete nucleotide sequence of strawberry vein banding virus (SVBV) has been determined and bioinformatic analysis has revealed that the SVBV genome could encode seven proteins, the precise function of each protein is unclear.
Peng-huan RUI, Zhan-qi WANG, Wen-shu SHAN, Wei-wei XIA, Xiu-hong ZHOU, Lian-lian YANG, Lei JIANG, Tong JIANG   +7 more
doaj  

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source