Results 191 to 200 of about 6,491,357 (404)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Comparative Genome Analysis of Old World and New World TYLCV Reveals a Biasness toward Highly Variable Amino Acids in Coat Protein. [PDF]

Plants (Basel), 2023
Nigam D, Muthukrishnan E, Flores-López LF, Nigam M, Wamaitha MJ.   +4 more
europepmc   +1 more source

The Coat Protein Is Dispensable for the Establishment of Systemic Infections by Pea Enation Mosaic Enamovirus

, 1997
Jihad Skaf, D. G. Rucker, S. A. Demler, Christiane E. Wobus, G. A. de Zoeten   +4 more
openalex   +2 more sources

A Coat Protein on Phagosomes Involved in the Intracellular Survival of Mycobacteria

Cell, 1999
G. Ferrari, H. Langen, M. Naito, J. Pieters   +3 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Extended Plasmonic Nanostructures Templated by Tobacco Mosaic Virus Coat Protein. [PDF]

Small
Abu-Baker I, Al-Feghali A, Zolfaghar E, Velpula G, Biela AP, De Feyter S, Heddle JG, Cosa G, Blum AS.   +8 more
europepmc   +1 more source

Formation of synthetic RNA protein granules using engineered phage-coat-protein -RNA complexes. [PDF]

Nat Commun, 2022
Granik N, Katz N, Willinger O, Goldberg S, Amit R.   +4 more
europepmc   +1 more source

The Coat Protein of Turnip Crinkle Virus Suppresses Posttranscriptional Gene Silencing at an Early Initiation Step

Journal of Virology, 2003
F. Qu, T. Ren, T. J. Morris
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Discovery of bioactive inhibitors targeting onion yellow dwarf virus coat protein based on molecular docking and simulation. [PDF]

BMC Plant Biol
Irfan A, Awan MF, Naz Q, Sarwar MF, Mujwar S, Mubeen I, Obaidur Rab S.   +6 more
europepmc   +1 more source