Results 121 to 130 of about 1,381,766 (368)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Solid and liquid oxidation products have been considered to be the key issues to influence the ablation resistance of UHTCs coatings. However, the effect of solid oxidation products on the ablation performance is not clear.
Yixiang Xu+6 more
doaj
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Mixed polyvalent-monovalent metal coating for carbon-graphite fibers [PDF]
An improved coating of gasification catalyst for carbon-graphite fibers is provided comprising a mixture of a polyvalent metal such as calcium and a monovalent metal such as lithium.
Harper-Tervet, J.+2 more
core +1 more source
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel+4 more
wiley +1 more source
This work treats the behavior of a glass fibre/unsaturated polyester (UP) composite with structural defects subjected to the attack of two corrosive solutions: H2SO4 and NaOH.
Nabila Belloul+3 more
doaj +1 more source
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
In vitro toxicity of nanoceria: effect of coating and stability in biofluids [PDF]
Due to the increasing use of nanometric cerium oxide in applications, concerns about the toxicity of these particles have been raised and have resulted in a large number of investigations. We report here on the interactions between 7 nm anionically charged cerium oxide particles and living mammalian cells.
arxiv
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
Production of a High Resolving Power by means of Multilayer Coatings [PDF]
A. H. Jarrett
openalex +1 more source