Results 91 to 100 of about 43,643 (334)

Cobalamin Status from Pregnancy to Early Childhood: Lessons from Global Experience.

Advances in Nutrition, 2017
Low cobalamin intake and status during pregnancy or lactation have been linked to adverse maternal and perinatal health outcomes, whereas low cobalamin status during early childhood is associated with impaired development in children.
R. Obeid, M. Murphy, Pol Solé-Navais, C. Yajnik   +3 more
semanticscholar   +1 more source

Successful treatment of Pseudescherichia vulneris‐associated acute haemorrhagic diarrhoea with a single faecal microbiota transplantation in a dog

Veterinary Record Case Reports, EarlyView.
Abstract An 8‐year‐4‐month‐old, female, neutered labrador retriever with acute haemorrhagic diarrhoea was unresponsive to symptomatic and antibiotic treatment, and developed gastrointestinal protein loss leading to significant hypoalbuminaemia.
Luis Miguel Garcia Roldan, Glynn Woods, Julien Dandrieux, Silke Salavati Schmitz   +3 more
wiley   +1 more source

Cobalamin Malabsorption due to a Dysfunctional Intrinsic Factor

Canadian Journal of Gastroenterology, 1989
An 18-year-old French Canadian student presenting with a severe normocytic anemia, had undetectable serum cobalamin but normal gastric acidity and no evidence of generalized malabsorption. The gastric juice contained a normal quantity of intrinsic factor.
Jeanne Drouin, Nadia Mikhael
doaj   +1 more source

Infant Serum and Maternal Milk Vitamin B-12 Are Positively Correlated in Kenyan Infant-Mother Dyads at 1-6 Months Postpartum, Irrespective of Infant Feeding Practice. [PDF]

, 2018
BackgroundVitamin B-12 is an essential nutrient required for many functions including DNA synthesis, erythropoiesis, and brain development. If maternal milk vitamin B-12 concentrations are low, infants may face elevated risks of deficiency when ...
Achando, Beryl, Allen, Lindsay H, Chantry, Caroline J, Hampel, Daniela, Kiprotich, Marion, Lin, Audrie, Null, Clair A, Shahab-Ferdows, Setareh, Stewart, Christine P, Williams, Anne M   +9 more
core   +3 more sources

Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin

Journal of Biological Chemistry, 2017
Riboswitches are a widely distributed class of regulatory RNAs in bacteria that modulate gene expression via small-molecule-induced conformational changes.
J. Polaski, Samantha M. Webster, J. E. Johnson, R. Batey   +3 more
semanticscholar   +1 more source

Primary renal potassium wasting syndrome in a juvenile domestic medium‐hair cat secondary to an atypical distal renal tubular disorder of undetermined molecular origin

Veterinary Record Case Reports, EarlyView.
Abstract Renal potassium wasting syndromes, such as Gitelman's syndrome (GS), are well documented in humans but rarely reported in veterinary medicine. This case describes a 6‐month‐old domestic medium‐hair cat presenting with chronic hypokalaemia, polyuria and polydipsia. Diagnostic evaluation revealed hypokalaemia, metabolic alkalosis, hypochloraemia
Kyle L. Granger Jr., Vivian Ojeda‐Rosenthal, Mei Lun Mui   +2 more
wiley   +1 more source

Cobalamin coenzyme forms are not likely to be superior to cyano‐ and hydroxyl‐cobalamin in prevention or treatment of cobalamin deficiency [PDF]

Molecular Nutrition & Food Research, 2015
Methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl) are coenzymes for methionine synthase and methylmalonyl‐CoA mutase, respectively. Hydroxylcobalamin (HOCbl) and cyanocobalamin (CNCbl) are frequently used for supplementation. MeCbl and AdoCbl have recently emerged as alternative forms in supplements. In the light of metabolic transformation of Cbl
Rima Obeid, Sergey N. Fedosov, Sergey N. Fedosov, Ebba Nexo   +3 more
openaire   +4 more sources

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]

, 2019
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R, Han, Andrew W, Jackson, Samantha N, Mok, Kenny C, Seth, Erica C, Shelton, Amanda N, Taga, Michiko E   +6 more
core   +1 more source

Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme.

Journal of the American Chemical Society, 2017
The biosynthesis of branched alkoxy groups, such as the unique t-butyl group found in a variety of natural products, is still poorly understood. Recently, cystobactamids were isolated and identified from Cystobacter sp as novel antibacterials.
Yuanyou Wang, Bastien Schnell, S. Baumann, R. Müller, T. Begley   +4 more
semanticscholar   +1 more source

Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities

Cell Proliferation, EarlyView.
ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou, Dongwei Liu, Zuishuang Guo, Cien Wei, Fengyu Cao, Yue Xu, Qi Feng, Fengxun Liu   +7 more
wiley   +1 more source