Results 121 to 130 of about 43,643 (334)
Decreased cobalamin sensitivity and biological aging acceleration in the general population
Background: The evidence on the association between cobalamin (Cbl) and aging or relevant outcomes is limited and controversial. We aimed to investigate the relationships between cobalamin intake- and function-related biomarkers and biological aging ...
Fan Tang+7 more
doaj
Effectiveness of the National Program of Complementary Feeding for older adults in Chile on vitamin B12 status in older adults; secondary outcome analysis from the CENEX Study (ISRCTN48153354). [PDF]
BACKGROUND: Older people are at increased risk of vitamin B12 deficiency and the provision of fortified foods may be an effective way to ensure good vitamin B12 status in later life.
Albala, Cecilia+4 more
core +1 more source
The figure illustrates how high plasma glutathione levels can promote the dethiolation of homocysteinylated proteins, leading to the release of homocysteine. The freed homocysteine is then either excreted through the kidneys or further processed via cellular metabolism, supporting homocysteine clearance and metabolic balance.
Daniela Giustarini+3 more
wiley +1 more source
Selective cobalamin malabsorption and the cobalamin-intrinsic factor receptor.
The disease is characterised by cobalamin (Cbl) deficiency in children 0-5 years old, causing failure to thrive, infections, megaloblastic anaemia, neuropathy, and mild general malabsorption; slight proteinuria is common. Cbl injections produce remission, but Cbl malabsorption and proteinuria persist. About 250 cases have been reported.
openaire +4 more sources
Metal homeostasis is central to all forms of life, as metals are es-sential micronutrients with toxic effects at elevated levels. Macromolecular machines facilitate metal uptake into the cells and their intracellular level is regulated by multiple means,
Julia Graf+4 more
doaj +1 more source
Microbial metabolism: optimal control of uptake versus synthesis [PDF]
Microbes require several complex organic molecules for growth. A species may obtain a required factor by taking up molecules released by other species or by synthesizing the molecule.
Frank, Steven A.
core +3 more sources
Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical Properties
Two ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and structural characterizations, which determine ferredoxin functionality and pathway specificity. The structure of FdC (PDB: 9I2A) and model of FdN (AF‐D5ARY6)
Holly Addison+5 more
wiley +1 more source
Investigating the origins of B12 biosynthesis in the most ancient roots of the tree of life [PDF]
Vitamin B12, also known as B12 or cobalamin, is a vital nutrient required across all branches of life, but the ability to synthesize this complex molecule de novo is limited to only a few archaea and bacteria.
Alicea, Edil+5 more
core
Mechanism of Cobalamin-Mediated Reductive Dehalogenation of Chloroethylenes
Reductive dehalogenation involving cobalamin has been proved to be a promising strategy for decontamination of the polluted environment. However, cob(I)alamin can act both as a strong reductant and a powerful nucleophile, and thus, several competing ...
Li Ji+4 more
semanticscholar +1 more source