Results 81 to 90 of about 43,643 (334)

Development of CHARMM-Compatible Force-Field Parameters for Cobalamin and Related Cofactors from Quantum Mechanical Calculations.

Journal of Chemical Theory and Computation, 2018
Corrinoid cofactors such as cobalamin are used by many enzymes and are essential for most living organisms. Therefore, there is broad interest in investigating cobalamin-protein interactions with molecular dynamics simulations.
A. Pavlova, Jerry M. Parks, J. Gumbart
semanticscholar   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal

Nutrients, 2018
Cobalamin and folate are crucial micronutrients during infancy and they are required for growth and cognitive development. Due to the monotonous and predominantly vegetarian-based complementary feeding and poor maternal micronutrient status, infants from
R. Chandyo, M. Ulak, I. Kvestad, M. Hysing, M. Shrestha, S. Ranjitkar, A. Ulvik, P. Ueland, L. Shrestha, T. Strand   +9 more
semanticscholar   +1 more source

Ecogenomics and limnological dynamics of a new Thiocapsa species blooming in the whole water column of a karstic lake

Limnology and Oceanography, EarlyView.
Abstract Purple sulfur bacteria (PSB) of the family Chromatiaceae (Gammaproteobacteria) can perform chemo‐ and photo‐lithoautotrophy (through anoxygenic photosynthesis) in anoxic layers of freshwater stratified (including meromictic) lakes. This group has been extensively studied via physiological and ecological approaches, albeit their genomics has ...
Pedro J. Cabello‐Yeves, Antonio Picazo, Carlos Rochera, Daniel Morant, Eduardo Vicente, David J. Scanlan, Richard J. Puxty, Antonio Camacho   +7 more
wiley   +1 more source

Serial Measurement of Serum Pancreatic Lipase Immunoreactivity, Feline Trypsin-like Immunoreactivity, and Cobalamin Concentrations in Kittens

Veterinary Sciences, 2022
Serum concentrations of feline pancreatic lipase immunoreactivity (fPLI), feline trypsin-like immunoreactivity (fTLI), and cobalamin are commonly used for the diagnostic investigation of cats with gastrointestinal signs.
Evangelia M. Stavroulaki, Kassiopi Christina G. Kokkinaki, Manolis N. Saridomichelakis, Jörg M. Steiner, Jonathan A. Lidbury, Panagiotis G. Xenoulis   +5 more
doaj   +1 more source

A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias [PDF]

, 2017
CONTEXT: This paper reports on the results of treatment of compressive neuralgia using a combination of nucleotides (uridine triphosphate trisodium [UTP] and cytidine monophosphate disodium [CMP]) and vitamin B(12).
Buchman, Luiz, Geller, Mauro, Goldberg, Henrique, Goldberg, Stephanie Wrobel, Mezitis, Spyros GE, Mibielli, Marco Antonio, Nunes, Carlos Pereira, Oliveria, Lisa, Rzetelna, Helio, Wajnsztajn, Fernanda   +9 more
core   +2 more sources

Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.

Journal of NutriLife, 2018
Background Formate is produced in mitochondria via the catabolism of serine, glycine, dimethylglycine, and sarcosine. Formate produced by mitochondria may be incorporated into the cytosolic folate pool where it can be used for important biosynthetic ...
Luke Macmillan, G. Tingley, S. K. Young, K. Clow, E. Randell, M. Brosnan, J. Brosnan   +6 more
semanticscholar   +1 more source

Efficient cobalamin uptake and cycling contribute to the lack of cobalamins in the surface cobalt‐binding ligand pool in the North Pacific

Limnology and Oceanography Letters, EarlyView.
Abstract Cobalt is a central component of cobalamins, which are nutrients essential for various metabolic processes in marine organisms. Dissolved cobalt in seawater is mostly bound to organic ligands, and the prevailing assumption to date is that these ligands are cobalamin‐related compounds, yet the identity and impact of these ligands on cobalt ...
Jiwoon Park, Katherine R. Heal, Anitra E. Ingalls, Ryan D. Groussman, Zinka Bartolek, E. Virginia Armbrust, Randelle M. Bundy   +6 more
wiley   +1 more source

Serum Cobalamin and Methylmalonic Acid Concentrations in Hyperthyroid Cats Before and After Radioiodine Treatment

Journal of Veterinary Internal Medicine, 2016
Background Hyperthyroidism, the most common endocrine disorder in cats, has been associated with low serum cobalamin concentrations. Whether this is a functional cobalamin deficiency of clinical importance has not been assessed.
B.M. Geesaman, W.H. Whitehouse, K.R. Viviano   +2 more
doaj   +1 more source

An ecological framework for microbial metabolites in the ocean ecosystem

Limnology and Oceanography Letters, EarlyView.
Abstract The ocean microbe‐metabolite network involves thousands of individual metabolites that encompass a breadth of chemical diversity and biological functions. These microbial metabolites mediate biogeochemical cycles, facilitate ecological relationships, and impact ecosystem health. While analytical advancements have begun to illuminate such roles,
Bryndan P. Durham, Winifred M. Johnson, Catherine C. Bannon, Erin M. Bertrand, Anitra E. Ingalls, Bethanie R. Edwards, Amy Apprill, Angela K. Boysen, Randelle M. Bundy, Huan Chen, Frank X. Ferrer‐González, Cara Fiore, Katherine R. Heal, Constanze Kuhlisch, Shuting Liu, Kaijun Lu, Laurel E. Meke, Sammy Pontrelli, Prabavathy Vaiyapuri Ramalingam, Alicia M. Reigel, Joshua S. Sacks, Jeremy E. Schreier, Jegan Sekar, Mario Uchimiya, Elizabeth B. Kujawinski   +24 more
wiley   +1 more source