Results 91 to 100 of about 6,638 (137)

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

Journal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

A cobalt concentration sensitive Btu-like system facilitates cobalamin uptake in Anabaena sp. PCC 7120

Microbial Cell
Metal homeostasis is central to all forms of life, as metals are es-sential micronutrients with toxic effects at elevated levels. Macromolecular machines facilitate metal uptake into the cells and their intracellular level is regulated by multiple means,
Julia Graf, Leonard Fresenborg, Hans-Michael Seitz, Rafael Pernil, Enrico Schleiff   +4 more
doaj   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Pernicious anemia is a common cause of cobalamin deficiency-caused megaloblastic anemia in Hainan, China

Hematology
Background Pernicious anemia (PA) is believed to be highly prevalent in Western countries but has rarely been reported in China. The study explores whether PA, an autoimmune disease, is an uncommon cause of cobalamin (vitamin B12) deficiency anemia in ...
Meixiao Shen, Xiansheng Luo, Cuiyun Wu, Juan Wang, Zhiming Wang, Meiqing Lei   +5 more
doaj   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3959-3971, November 2026.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Growth, Carcass Quality and Gut Microbiota Responses to Extruded Rapeseed Meal With Protease in Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
The 5%–7.5% extruded rapeseed meal improved broiler growth, nutrient digestibility, carcass traits, intestinal morphology and gut microbial balance. ABSTRACT Background Soybean meal (SBM) is a major protein source in broiler diets, but its cost and dependence on a limited number of protein sources have increased interest in alternative feed ingredients.
Rohban Hameed, Muhammad Tahir, Rifat Ullah Khan, Sohail Ahmad, Luciana Rossi, Rasha K. Al‐Akeel   +5 more
wiley   +1 more source

Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging

, 2016
Fluorescent derivatives of cobalamin have been prepared by linking fluorophores to cobalamin through a propylamide spacer. Fluorescein, naphthofluorescein, and Oregon Green derivatives have been prepared in good yield by reaction of the fluorophore NHS ...
Patrick R. Pinson (3063399), Michelle J. Cannon (3063393), Charles B. Grissom (2368081), John D. Munger (3063402), Claudia C. Smeltzer (3063396), Frederick G. West (2944569)   +5 more
core   +1 more source

Protease and Phytase Alleviate Digestive Limitations of Canola Seed in Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Protease and phytase, especially in combination, counteracted the digestive limitations of 10% canola seed in broiler diets by improving nutrient utilisation, intestinal health, microbial balance, digesta viscosity, bone quality and growth performance.
Ramazan Sheikh‐Nazari, Kaveh Jafari‐Khorshidi, Mohammad Ali Jafari   +2 more
wiley   +1 more source